Drug transporters : molecular characterization and role in drug disposition / [electronic resource]
edited by Guofeng You, Marilyn E. Morris.
- Second edition.
- 1 online resource.
- Wiley series in drug discovery and development .
- Wiley series in drug discovery and development. .
Includes bibliographical references and index.
Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development.
9781118705049 (pdf) 1118705041 (pdf) 9781118705209 (epub) 1118705203 (epub) 9781118705308 1118705300 9781118704981 1118704983 1118489934 9781118489932
2014009508
Carrier proteins.
Drug carriers (Pharmacy)
SCIENCE--Life Sciences--Anatomy & Physiology.
Carrier proteins.
Drug carriers (Pharmacy)
Biological Transport--physiology.
Membrane Transport Proteins--physiology.
Pharmacokinetics.
Pharmakokinetik.
Arzneimittel.
Chemische Synthese.
Arzneimittelwechselwirkung.
Electronic books.
Electronic books.
R857.B52
571.6/4
QU 120
Includes bibliographical references and index.
Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development.
9781118705049 (pdf) 1118705041 (pdf) 9781118705209 (epub) 1118705203 (epub) 9781118705308 1118705300 9781118704981 1118704983 1118489934 9781118489932
2014009508
Carrier proteins.
Drug carriers (Pharmacy)
SCIENCE--Life Sciences--Anatomy & Physiology.
Carrier proteins.
Drug carriers (Pharmacy)
Biological Transport--physiology.
Membrane Transport Proteins--physiology.
Pharmacokinetics.
Pharmakokinetik.
Arzneimittel.
Chemische Synthese.
Arzneimittelwechselwirkung.
Electronic books.
Electronic books.
R857.B52
571.6/4
QU 120