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Translational systems biology : concepts and practice for the future of biomedical research / (Record no. 246968)

000 -LEADER
fixed length control field 05143cam a2200505Ii 4500
001 - CONTROL NUMBER
control field ocn893128253
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20190328114809.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cnu---unuuu
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 141016t20142015ne o 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency N$T
Language of cataloging eng
Description conventions rda
-- pn
Transcribing agency N$T
Modifying agency YDXCP
-- UKMGB
-- UIU
-- OCLCF
-- EBLCP
-- OCLCQ
-- DEBSZ
-- OCLCQ
-- U3W
-- MERUC
-- D6H
-- OCLCQ
-- WYU
016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER
Record control number 016911996
Source Uk
016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER
Record control number 016914121
Source Uk
019 ## -
-- 893332896
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780123978905
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 0123978904
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Canceled/invalid ISBN 9780123978844
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)893128253
Canceled/invalid control number (OCoLC)893332896
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH324.2
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 007000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.80285
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Vodovotz, Yoram,
Relator term author.
245 10 - TITLE STATEMENT
Title Translational systems biology : concepts and practice for the future of biomedical research /
Medium [electronic resource]
Statement of responsibility, etc. Yoram Vodovotz, Gary An.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Amsterdam :
Name of producer, publisher, distributor, manufacturer Academic Press, an imprint of Elsevier,
Date of production, publication, distribution, manufacture, or copyright notice [2014]
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice �2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
588 0# - SOURCE OF DESCRIPTION NOTE
Source of description note Online resource; title from PDF title page (EBSCO, viewed October 16, 2014).
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Front Cover; Translational Systems Biology; Copyright Page; Dedication; Contents; Preface; Acknowledgments; I. Introduction and Overview; 1.1 Interesting Times: The Translational Dilemma and the Need for Translational Systems Biology of Inflammation; Primary Goal: Facilitate the Translation of Basic Biomedical Research to the Implementation of Effective Clinical Therapeut ... ; How to Approach This Book; References; II. The Current Landscape: Where It Came From, How We Got Here, and What Is Wrong.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 2.1 A Brief History of the Philosophical Basis of the Scientific Endeavor: How We Know What We Know, and How to Know MoreModels in the Cave; Earth at the Center: A Reasonable Mistake, and an Unreasonable Perpetuation; The Scientific Method of Francis Bacon; Newton: The (Justifiable) Origins of Physics Envy; The Problem of Induction: Hume's Empiricism; Logic and Its True/False Promise: Logical Positivism, Godel and Popper; Charles Peirce Suggests Taking a Guess: The Abductive Approach; The Mapping Problem: Back to Plato?; Suggested Additional Readings.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 2.2 A Brief History of Biomedical Research up to the Molecular Biology RevolutionReference; Suggested Additional Readings; 2.3 Biomedical Research Since the Molecular Revolution: An Embarrassment of Riches; References; 2.4 Randomized Clinical Trials: A Bridge Too Far?; References; 2.5 Complexity in Biomedical Research: Mysticism Versus Methods; References; Suggested Additional Readings; 2.6 Human Nature, Politics, and Translational Inertia; Setting the Table with Bacon; An Embarrassment of Riches; Shibboleths in Science: The Problem with Pedigrees.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note Incentives and the Professionalization of ScienceDeep Pockets, with Holes: The Pharma Conundrum; Reference; III. Translational Systems Biology: How We Propose to Fix the Problems of the Current Biomedical Research Landscape; 3.1 Towards Translational Systems Biology of Inflammation; Primary Goal: Facilitate the Translation of Basic Biomedical Research to the Implementation of Effective Clinical Therapeut ... ; References; 3.2 Dynamic Knowledge Representation and the Power of Model Making; References.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 3.3 A Roadmap for a Rational Future: A Systematic Path for the Design and Implementation of New TherapeuticsRational Evaluation of Drug Candidates: Knowing What Might Work, and More Importantly, What Won't; In silico Clinical Trials: Crossing the "Bridge Too Far"; From Populations to Individuals: Personalizing Medical Care; References; IV. Tools and Implementation of Translational Systems Biology: This is How We Do It; 4.1 From Data to Knowledge in Translational Systems Biology: An Overview of Computational Approaches Across the Scientific ...
520 ## - SUMMARY, ETC.
Summary, etc. Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money's worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the inte.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Systems biology.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element SCIENCE
General subdivision Life Sciences
-- Biochemistry.
Source of heading or term bisacsh
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Systems biology.
Source of heading or term fast
Authority record control number (OCoLC)fst01745552
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name An, Gary,
Relator term author.
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Print version:
Main entry heading Vodovotz, Yoram.
Title Translational Systems Biology : Concepts and Practice for the Future of Biomedical Research.
Place, publisher, and date of publication Burlington : Elsevier Science, �2014
International Standard Book Number 9780123978844
856 40 - ELECTRONIC LOCATION AND ACCESS
Materials specified ScienceDirect
Uniform Resource Identifier http://www.sciencedirect.com/science/book/9780123978844

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