Interpreting biomedical science : experiment, evidence, and belief / (Record no. 247104)
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| control field | ocn911179264 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190328114811.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150618s2015 enk ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | N$T |
| Language of cataloging | eng |
| Description conventions | rda |
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| Transcribing agency | N$T |
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| 019 ## - | |
| -- | 911247236 |
| -- | 912406001 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780124199569 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0124199569 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0124186890 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780124186897 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780124186897 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)911179264 |
| Canceled/invalid control number | (OCoLC)911247236 |
| -- | (OCoLC)912406001 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R852 |
| 060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | 2015 J-145 |
| 060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | W 20.5 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 106000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610.72 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maiv�ali, �Ulo, |
| Relator term | author. |
| 245 10 - TITLE STATEMENT | |
| Title | Interpreting biomedical science : experiment, evidence, and belief / |
| Medium | [electronic resource] |
| Statement of responsibility, etc. | �Ulo Maiv�ali. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | London : |
| Name of producer, publisher, distributor, manufacturer | Academic Press is an imprint of Elsevier, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Online resource; title from PDF title page (Ebsco, viewed June 19, 2015). |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Interpreting Biomedical Science: Experiment, Evidence, and Belief discusses what can go wrong in biological science, providing an unbiased view and cohesive understanding of scientific methods, statistics, data interpretation, and scientific ethics that are illustrated with practical examples and real-life applications. Casting a wide net, the reader is exposed to scientific problems and solutions through informed perspectives from history, philosophy, sociology, and the social psychology of science. The book shows the differences and similarities between disciplines and different eras and illustrates the concept that while sound methodology is necessary for the progress of science, we cannot succeed without a right culture of doing things. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; Interpreting Biomedical Science: Experiment, Evidence, and Belief; Copyright Page; Contents; Preface; Acknowledgments; Introduction; Science Made Easy; Did the Greeks Get their Math Right but their Science Wrong?; The Scientific Revolution; Deduction and Induction as Two Approaches to Scientific Inference; References; I. What Is at Stake: The Skeptical Argument; 1 Do We Need a Science of Science?; 1.1 Are We Living in the Golden Age of Science?; 1.2 R & D and the Cost of Medicine; 1.3 The Efficiency of Drug Discovery; 1.4 Factors that Endanger the Quality of Medical Evidence. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1.5 The Stability of Evidence-Based Medical Practices1.6 Reproducibility of Basic Biomedical Science; 1.6.1 Genome-Wide Association Studies; 1.6.2 Microarray Studies; 1.6.3 Proteomics; 1.6.4 Small Science; 1.7 Is Reproducibility a Good Criterion of Quality of Research?; 1.8 Is Biomedical Science Self-Correcting?; 1.9 Do We Need a Science of Science?; References; 2 The Basis of Knowledge: Causality and Truth; 2.1 Scientific Realism and Truth; 2.2 Hume's Gambit; 2.3 Kant's Solution; 2.4 Why Induction Is Poor Deduction; 2.5 Popper's Solution; 2.6 Why Deduction Is Poor Induction. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.7 Does Lung Cancer Cause Smoking?2.8 Correlation, Concordance, and Regression; 2.8.1 Correlation; 2.8.2 Concordance; 2.8.3 Regression; 2.9 From Correlation to Causation; 2.10 From Experiment to Causation; 2.11 Is Causality a Scientific Concept?; References; II. The Method; 3 Study Design; 3.1 Why Do Experiments?; 3.2 Population and Sample; 3.3 Regression to the Mean; 3.4 Why Repeat an Experiment?; 3.5 Technical Versus Biological Replication of Experiments; 3.6 Experimental Controls; 3.6.1 Example 1. Negative Controls; 3.6.2 Example 2. Normalization Controls. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3.6.3 Example 3. Controlling the Controls3.7 Multiplicities; 3.8 Conclusion: How to Design an Experiment; References; 4 Data and Evidence; 4.1 Looking at Data; 4.2 Modeling Data; 4.3 What Is Probability?; 4.3.1 Bayesian Probability; 4.3.2 Frequentist Probability; 4.3.3 Propensity Theory of Probability; 4.4 Assumptions Behind Frequentist Statistical Tests; 4.5 The Null Hypothesis; 4.6 The P value; 4.6.1 What the P Value Is Not; 4.7 Neyman-Pearson Hypothesis Testing; 4.8 Multiple Testing in the Context of NPHT; 4.9 P Value as a Measure of Evidence; 4.10 The "Error Bars." |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4.11 Likelihood as an Unbiased Measure of Evidence4.12 Conclusion: Ideologies Behind Some Methods of Statistical Inference; References; 5 Truth and Belief; 5.1 From Long-Run Error Probabilities to Degrees of Belief; 5.2 Bayes Theorem: What Makes a Rational Being?; 5.3 Testing in the Infinite Hypothesis Space: Bayesian Parameter Estimation; 5.4 All Against All: Bayesianism Versus Frequentism Versus Likelihoodism; 5.5 Bayesianism as a Philosophy; 5.6 Bayesianism and the Progress of Science; 5.7 Conclusion to Part II; References; III. The Big Picture; 6 Interpretation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine |
| General subdivision | Research |
| -- | Methodology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical sciences |
| General subdivision | Research. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Research. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical sciences |
| General subdivision | Research. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst01014611 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine |
| General subdivision | Research |
| -- | Methodology. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst01015079 |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedical Research. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Research Design. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Philosophy. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | lcgft |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Maiv�ali, �Ulo. |
| Title | Interpreting Biomedical Science : Experiment, Evidence, and Belief. |
| Place, publisher, and date of publication | Burlington : Elsevier Science, �2015 |
| International Standard Book Number | 9780124186897 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | http://www.sciencedirect.com/science/book/9780124186897 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | https://www.sciencedirect.com/science/book/9780124186897 |
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