RNA interference : application to drug discovery and challenges to pharmaceutical development / [electronic resource]
by Johnson, Paul H; Wiley InterScience (Online service).
Material type:
BookPublisher: Hoboken : John Wiley & Sons, ©2011Description: xvi, 450 pages : illustrations.ISBN: 9780470923733; 0470923733.Subject(s): Drug development | RNA editing | Drug development | RNA editing | Electronic booksOnline resources: Wiley Online Library Includes bibliographical references and index.
Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index.
Electronic reproduction. Hoboken, N.J. : Wiley InterScience, 2011. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Jan. 4, 2011). Access may be restricted to users at subscribing institutions.
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