Cancer epigenetics : biomolecular therapeutics in human cancer / [electronic resource]
by Giordano, Antonio, MD; Macaluso, Marcella; Wiley InterScience (Online service).
Material type: BookPublisher: Hoboken, N.J. : Wiley-Blackwell, ©2011Description: 1 online resource (pages).ISBN: 9781118005743; 1118005740; 9780471710967; 0471710962.Subject(s): Cancer -- Genetic aspects | Cancer -- Treatment | Epigenesis | DNA -- Methylation | Neoplasms -- genetics | Neoplasms -- therapy | DNA Methylation | Drug Design | Epigenesis, Genetic | Histones -- metabolism | Cancer -- Genetic aspects | Cancer -- Treatment | DNA -- Methylation | Epigenesis | Electronic booksOnline resources: Wiley Online LibraryIncludes bibliographical references.
Frontmatter -- Color Plates -- Section I: Epigenetics and Cell Cycle. Epigenetic Modulation of Cell Cycle: An Overview / Micaela Montanari, Antonio Giordano, Marcella Cintorino, Marcella Macaluso -- Section II: Epigenetics and Cell Development, Senescence and Differentiation. Epigenetics in Skeletal Muscle Development / Cristina Giacinti, Antonio Giordano -- Epigenetic Control in Cellular Senescence / Heike Helmbold, Wolfgang Deppert, Wolfgang Bohn -- Epigenetic Modulation in Cell Development and Differentiation / Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca, Francesca Pentimalli -- Section III: Epigenetics and Gene Transcription. Epigenetic Control of Gene Transcription / Christian Bronner, Mayada Achour, Thierry Chataigneau, Vaľrie B Schini-Kerth -- Epigenetics, MicroRNAs, and Cancer: An Update / Giuseppe Russo, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia Cito, Debora Muresu, Flavio Rizzolio, Antonio Giordano -- Section IV: Epigenetics and Cancer. The Role of Epigenetic Modifications in Cancer / Michael J Powell, Vladimir M Popov, Xiang Wang, Steven B McMahon, Alexander Mazo, Richard G Pestell -- MBD4/MED1 Protein in DNA Repair and Demethylation, Cancer, and Other Diseases / Serena Buontempo, Mara Sannai, Alfonso Bellacosa -- Epigenetics in Pediatric Cancers / Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, Rossella Rota -- Epigenetic Mechanisms in Cancer Formation and Progression / Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, Michele Maio -- Section V: Epigenetics and Anticancer Drug Development and Therapy. Recent Advances in the Field of Stem Cell Research: Toward the Definition of the Epigenetic and Genetic Codes of Pluripotency / Gaetano Romano -- Potential of Heat Shock Protein Targeting for Human Therapy / Laszlo Otvos -- Advances in Stem Cell Therapy for Cancer Research / Andrew Puca, Antonio Giordano -- Epigenetic Targets and Drug Development / Paraskevi Vogiatzi, Maria Irene Scarano, Pier Paolo Claudio -- Index.
(Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? / by Micaela Montanari, Antonio Giordano, Marcella Cintorino and Marcella Macaluso -- Section II: Epigenetics and Cell Development, Senescence and Differentiation -- Epigenetic in skeletal muscle Development? / by Cristina Giacinti and Antonio Giordano -- Epigenetic control in cellular senescence? / by Heike Helmbold, Wolfgang Deppert, and Wolfgang Bohn -- Epigenetic modulation in cell development and differentiation? / by Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca and Francesca Pentimalli -- Section III: Epigenetics and Gene Transcription -- Epigenetic control of gene transcription? / by Christian Bronner, Mayada Achour, Thierry Chataigneau and Valerie B. Schini-Kerth -- Epigenetics, microRNAs and cancer: an update? / by Giuseppe Russo1, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia Cito, Debora Muresu, Flavio Rizzolio and Antonio Giordano -- Section IV: Epigenetics and Cancer -- Epigenetics and Cancer? by Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon, Alexander Mazo, and Richard G. Pestell.
The MBD4/MED1 Protein in DNA Repair, DNA Demethylation, Disease and Cancer? / Serena Buontempo, Mara Sannai and Alfonso Bellacosa -- Epigenetics in pediatric cancers? by Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, Rossella Rota -- Epigenetic mechanisms in cancer formation and progression? by Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, Michele Maio -- Section V: Epigenetics and Anticancer Drug Development and Therapy -- Recent advances in the field of stem cell research: towards the definition of the epigenetic and genetic codes of pluripotency? / by Gaetano Romano -- Potential of Heat Shock Protein Targeting for Human Therapy? / by Laszlo Otvos, Jr -- Advancements in Stem Cell Therapy & Research? /by Andrew Puca and Antonio Giordano.
"Biomolecular Therapeutics for Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences"--Provided by publisher.
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