HIV-1 integrase : mechanism and inhibitor design / [electronic resource]
by Neamati, Nouri [edt].
Material type:
BookSeries: Wiley series in drug discovery and development: Publisher: Hoboken, N.J. : Wiley, ©2011Description: 1 online resource (xiii, 506 pages, [16] pages of plates) : illustrations (some color).ISBN: 9781118015377; 1118015371; 9781118015353; 1118015355.Subject(s): HIV (Viruses) -- Enzymes | HIV (Viruses) -- Enzymes -- Inhibitors | Antiviral agents | HIV Integrase Inhibitors -- pharmacology | Drug Design | HIV Integrase | Antiviral agents | HIV (Viruses) -- Enzymes -- Inhibitors | HIV (Viruses) -- Enzymes | HEALTH & FITNESS -- Diseases -- AIDS & HIV | MEDICAL -- AIDS & HIV | Electronic booksOnline resources: Wiley Online Library Summary: This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1.
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Includes bibliographical references and index.
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1.
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