Includes bibliographical references and index.

Front Matter -- Supplemental Images -- Transplantation Immunobiology. The Immune Response to a Transplanted Organ: An Overview / Fadi G Lakkis -- Antigen Presentation in Transplantation / Martin H Oberbarnscheidt, Fadi G Lakkis -- The T Cell Response to Transplantation Antigens / Didier A Mandelbrot, Bryna Burrell, Mohamed H Sayegh, Peter S Heeger -- The B Cell Response to Transplantation Antigens / Roger Sciammas, Anita S Chong, Robert B Colvin -- The Innate Response to a Transplanted Organ / Daniel R Goldstein, Laurence A Turka -- Regulation of the Alloimmune Response / Kathryn J Wood, Terry B Strom -- Transplantation Clinical Pharmacology. Pharmacokinetics / Venkateswaran C Pillai, Raman Venkataramanan -- Therapeutic Drug Monitoring for Immunosuppressive Agents / Michael C Milone, Leslie M J Shaw -- Pharmacometrics: Concepts and Applications to Drug Development / Mallika Lala, Jogarao V S Gobburu -- Pharmacogenomics and Organ Transplantation / Gilbert J Burckart, Richard M Watanabe -- Study Design/Process of Development: Clinical Studies / Richard D Mamelok -- Agents. Corticosteroids / Olivia R Blume, Sarah E Yost, Bruce Kaplan -- Azathioprine / Barry J Browne -- Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate / David Hager, Arjang Djamali, Bruce Kaplan -- Cyclosporine: Molecular Action to Clinical Therapeutics / Bradford Strijack, Paul A Keown -- Tacrolimus / William E Fitzsimmons -- Inhibitors of Mammalian Target of Rapamycin / Barry D Kahan -- Inhibitors Targeting JAK3 / Gary Chan, Paul S Changelian -- Cyclophosphamide / John J Curtis -- Application of Antisense Technology in Medicine / Beata Mierzejewska, Stanislaw M Stepkowski -- The Role of Ganciclovir in Transplantation / Lyndsey J Bowman, Daniel C Brennan -- Transplantation Immunotherapy with Antithymocyte Globulin (ATG) / John L Dzuris, Christian Bloy, Melanie Ruzek, John M Williams -- The Role of Alemtuzumab in Solid Organ Transplantation / Avinash Agarwal, David Bruno, Stuart J Knechtle -- Rituximab, an Anti-CD20 Monoclonal Antibody / Mark D Pescovitz -- The Anti-Interleukin 2 Receptor Antibodies / Muna Alnimri, Flavio Vincenti -- Infliximab/Anti-TNF / Marina Vardanyan, Edward C Parkin, Horacio L Rodriguez Rilo -- CTLA4-Ig / Sarah E Yost, Bruce Kaplan -- Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade / Swetha K Srinivasan, Helen L Triemer, Allan D Kirk -- Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation / Stanley C Jordan, Mieko Toyoda, Joseph Kahwaji, Alice Peng, Ashley A Vo -- Index.