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Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds / [electronic resource]

by Dörwald, Florencio Zaragoza.
Material type: materialTypeLabelBookPublisher: Weinheim : Wiley-VCH Verlag GmBH & Co., [2012]Description: 1 online resource (xvi, 605 pages) : illustrations.ISBN: 9783527645640; 3527645640; 9783527645664; 3527645667.Subject(s): Pharmaceutical chemistry | MEDICAL -- Drug Guides | MEDICAL -- Nursing -- Pharmacology | MEDICAL -- Pharmacology | MEDICAL -- Pharmacy | Pharmaceutical chemistry | Electronic books | Electronic booksOnline resources: Wiley Online Library
Contents:
pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.
Summary: Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.
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Includes bibliographical references and index.

pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.

Online resource; title from home page (viewed May 23, 2014).

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