Includes bibliographical references and index.

Cover; Title Page; Copyright; List of contributors; Preface; PART I: UPPER GI TRACT; Chapter 1: Prokinetic agents and antiemetics; Prokinetics; Antiemetic agents; Recommended reading; Chapter 2: Proton pump inhibitors; Introduction; Mechanism of action, pharmacodynamics, kinetics; Clinical use and dosing; Adverse effects/safety; Recommended reading; Chapter 3: Histamine H2-receptor antagonists; Introduction; Mechanism of action; Pharmacology; Clinical effectiveness; Adverse events; Recommended reading; Chapter 4: Prostaglandins and other mucosal protecting agents; Introduction of drug class.

Physicochemical propertiesFormulations and recommended dosages; Mechanism of action; Drug interactions; Pharmacokinetics; Clinical effectiveness; Toxicity; Pregnancy classes; Other mucosal protecting agents; Recommended reading; PART II: SMALL AND LARGE INTESTINE; Chapter 5: 5-HT modulators and other antidiarrheal agents and cathartics; Introduction; 5-HT modulators used in the management of GI disorders; 5-HT agents approved in the US for specific GI indications; Medications used for the treatment of chronic constipation; Medications used for the treatment of narcotic-induced constipation.

Antidiarrheal agentsConclusion; Recommended reading; Chapter 6: 5-aminosalicylates; Introduction; Preparations; Clinical use and efficacy; Pharmacology: preparations and dosing; Mechanism of action; Bioavailability and metabolism; Adverse effects and toxicity; Pregnancy (Table 6.7); Drug interactions (package inserts); Precautions and contraindications (Table 6.8); Special considerations: effectiveness in colorectal cancer prevention; Conclusion (Table 6.9); Recommended reading; Chapter 7: Immunosuppressive agents; Introduction; Thiopurines; Low-dose methotrexate (MTX); Calcineurin inhibitors.

Recommended readingChapter 8: Biological agents; Biological agents approved to treat IBD; Optimal treatment strategies with anti TNF therapies in IBD; Safety of biological agents in IBD; Emerging biologicals; Recommended reading; PART III: LIVER AND PANCREAS; Chapter 9: Interferons; Introduction; Mechanism of action; Pharmacology; Clinical effectiveness; Toxicity; Interferon types with generic and brand names; Pregnancy classes; Initial interferon dosing regimens for chronic hepatitis C; Recommended reading; Chapter 10: Nucleoside analogs; Introduction; Mechanism of action; Pharmacology.

Clinical effectivenessNucleoside analogs; Nucleotide analogs; Summary; Recommended reading; Chapter 11: Ursodeoxycholic acid, chelating agents, and zinc in the treatment of metabolic liver diseases; Ursodeoxycholic acid; Treatment of copper overload; Recommended reading; Chapter 12: Agents for the treatment of portal hypertension; Introduction; Nonselective beta-blockers (NSBB); Nitrates; Vasopressin analogs; Somatostatin analog; Midodrine; Albumin; Loop diuretics; Aldosterone antagonist; Aquaretics; Disaccharides; Antibiotics; Recommended reading; Chapter 13: Pancreatic enzymes; Introduction.

"Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: - Introduction of drug class, - Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations, - Dosing information for each GI condition and on- and off-label use, - Consistent use of both generic and trade names throughout, - Specific reference to drug use in pediatric patients and during pregnancy. Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists"--Provided by publisher.

Print version record and CIP data provided by publisher.