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Inorganic chemical biology : principles, techniques and applications / [electronic resource]

by Gasser, Gilles [editor.].
Material type: materialTypeLabelBookPublisher: Chichester, West Sussex : John Wiley & Sons Inc., 2014.Description: 1 online resource.ISBN: 9781118684153; 111868415X; 9781118684252; 1118684257; 9781118682975; 1118682971; 111851002X; 9781118510025.Subject(s): Chemistry, Inorganic | Biology, life sciences | Biochemical Phenomena | Metals -- chemistry | Macromolecular Substances -- chemistry | SCIENCE -- Life Sciences -- Biochemistry | Bioanorganische Chemie | Chemistry, Inorganic | Metals | Electronic books | Electronic booksOnline resources: Wiley Online Library
Contents:
New applications of immobilized metal ion affinity chromatography in chemical biology / Rachel Codd, Jiesi Gu, Najwa Ejje, Tulip Lifa -- Metal complexes as tools for structural biology / Michael D. Lee, Bim Graham and James D. Swarbrick -- AAS, XRF and MS methods in chemical biology of metal complexes / Ingo Ott, Christophe Biot and Christian Hartinger -- Metal complexes for cell and organism imaging / Kenneth Yin Zhang and Kenneth Kam-Wing Lo -- Cellular imaging with metal carbonyl complexes / Luca Quaroni and Fabio Zobi -- Probing DNA using metal complexes / Lionel Marclis, Willem Vanderlinden, Andre Kirsch De Mesmaeker -- Visualization of proteins and cells using dithiol-reactive metal complexes / Danielle Park, Ivan Ho Shon, Minh Hua, Vivien M. Chen, Philip J. Hogg -- Detection of metal ions, anions and small molecules using metal complexes / Qin Wang and Katherine J. Franz -- Photo-release of metal ions in living cells / Celina Gwizdala and Shawn C. Burdette -- Release of bioactive molecules using metal complexes / Peter Simpson and Ulrich Schatzschneider -- Metal complexes as enzyme inhibitors and catalysts in living cells / Julien Furrer, Gregory S. Smith and Bruno Therrien -- Other applications of metal complexes in chemical biology / Tanmaya Joshi, Malay Patra and Gilles Gasser.
Summary: Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology.
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Includes bibliographical references and index.

New applications of immobilized metal ion affinity chromatography in chemical biology / Rachel Codd, Jiesi Gu, Najwa Ejje, Tulip Lifa -- Metal complexes as tools for structural biology / Michael D. Lee, Bim Graham and James D. Swarbrick -- AAS, XRF and MS methods in chemical biology of metal complexes / Ingo Ott, Christophe Biot and Christian Hartinger -- Metal complexes for cell and organism imaging / Kenneth Yin Zhang and Kenneth Kam-Wing Lo -- Cellular imaging with metal carbonyl complexes / Luca Quaroni and Fabio Zobi -- Probing DNA using metal complexes / Lionel Marclis, Willem Vanderlinden, Andre Kirsch De Mesmaeker -- Visualization of proteins and cells using dithiol-reactive metal complexes / Danielle Park, Ivan Ho Shon, Minh Hua, Vivien M. Chen, Philip J. Hogg -- Detection of metal ions, anions and small molecules using metal complexes / Qin Wang and Katherine J. Franz -- Photo-release of metal ions in living cells / Celina Gwizdala and Shawn C. Burdette -- Release of bioactive molecules using metal complexes / Peter Simpson and Ulrich Schatzschneider -- Metal complexes as enzyme inhibitors and catalysts in living cells / Julien Furrer, Gregory S. Smith and Bruno Therrien -- Other applications of metal complexes in chemical biology / Tanmaya Joshi, Malay Patra and Gilles Gasser.

Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology.

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