Drug metabolism prediction / [electronic resource]
by Kirchmair, Johannes [editor.].
Material type:
BookSeries: Methods and principles in medicinal chemistry: Publisher: Weinheim, Germany : Wiley-VCH, 2014.Description: 1 online resource (538 pages) : illustrations.ISBN: 9783527673261; 3527673261; 3527672990; 9783527672998; 1306907993; 9781306907996; 3527335668; 9783527335664; 3527673016; 9783527673018; 3527673008; 9783527673001.Subject(s): Drugs -- Metabolism | Enzymes -- Effect of drugs on | MEDICAL -- Pharmacology | Drugs -- Metabolism | Enzymes -- Effect of drugs on | Electronic booksOnline resources: Wiley Online Library Includes bibliographical references at the end of each chapters and index.
Part 1. Introduction -- Part 2. Software, web servers and data resources to study metabolism -- Part 3. Computational approaches to study cytochrome P450 enzymes -- Part 4. Computational approaches to study sites and products of metabolism -- Part 5. Computational approaches to study enzymes inhibition and induction -- Part 6. Experimental approaches to study metabolism.
The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors.
Online resource; title from PDF title page (ebrary, viewed July 8, 2014).
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