Includes bibliographical references and index.

Molecular conduit between experience and dna: signalling cascade leading from maternal care to epigenetic programming 5.7. Reversibility of epigenetic programming by maternal care 5.8. Epigenetic programming by early life experience in humans; rRNA genes are hyper methylated in suicide victims who were abused as children 5.9. The response to early life adversity is broad and involves several gene networks 5.10. System wide responses to maternal deprivation; the impact of rearing differences in non-human primates 5.11. Natural disasters as a model to study the impact of maternal stress on child dna methylation 5.12. Summary References 6. Neurobiology and programming capacity of attachment learning to nurturing and abusive caregivers Tania L Roth, Gordon A Barr, Michael J Lewis, and Regina M Sullivan 6.1. Acknowledgments 6.2. Introduction 6.3. Infant attachment 6.4.

Conclusions References 8. Effects of genes and early experience on the development of primate behavior and stress reactivity Sean P. Coyne and Dario Maestripieri 8.1. Introduction 8.2. Assessment of infant behaviour and stress reactivity 8.3. Influence of naturally occurring variation in maternal style on offspring behaviour and stress reactivity 8.4. Main genetic effects on the development of infant behaviour and stress reactivity 8.5. Serotonin transporter gene (5htt) and its linked polymorphic region (5-httlpr) 8.6. The µ-opioid receptor gene (oprm1) 8.7. Dopamine receptor d4 (drd4) and other reward related genes 8.8. Summary and conclusions References 9. Institutional Deprivation and Neurobehavioral Development in Infancy Jenalee R. Doom & Megan R. Gunnar 9.1. Introduction 9.2. Cognition 9.3. Emotion 9.4. Behavior 9.5.

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"Environmental Experience and Plasticity of the Developing Brain goes beyond the genetic basis of neurodevelopment. Chapters illuminate the external factors that can dramatically impact the brain early in life and, consequently, the eventual accomplishment of developmental milestones and the construction of adult behavior and personality. Authored and edited by leaders in this rapidly growing field, Environmental Experience and Plasticity of the Developing Brain not only surveys preexisting literature on the effects of environment versus genetics, but also discusses more recent studies on the impacts of neurodevelopment in terms of maternal stimulation, environmental enrichment and sensory deprivation. The book also includes key examples of environmental impacts on preexisting genetic syndromes leading to developmental disabilities. Focus is also given to the consequences of early adverse experience in primates, as well as neurobiological and behavioral consequences in institutionalized human children and the reversibility of such consequences. Environmental Experience and Plasticity of the Developing Brain encompasses a broad area of research in the field of developmental neurobiology and offers a unique combination of different examples of environmental factors affecting brain development and behavior"--Provided by publisher.

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