An introduction to biotechnology : the science, technology and medical applications / [electronic resource]
by Godbey, W. T [author.].
Material type:
BookSeries: Woodhead Publishing series in biomedicine: Publisher: Amsterdam ; Academic Press, [2014]Description: 1 online resource : illustrations (chiefly color).ISBN: 9781908818485; 1908818484; 9781907568282; 190756828X.Subject(s): Biotechnology | SCIENCE -- Chemistry -- Industrial & Technical | TECHNOLOGY & ENGINEERING -- Chemical & Biochemical | Biotechnology | Bioengineering | Mechanical Engineering | Engineering & Applied Sciences | Electronic booksOnline resources: ScienceDirect | ScienceDirect Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed December 23, 2014).
An Introduction to Biotechnology is a biotechnology textbook aimed at undergraduates. It covers the basics of cell biology, biochemistry and molecular biology, and introduces laboratory techniques specific to the technologies addressed in the book; it addresses specific biotechnologies at both the theoretical and application levels.
Front Cover; An Introduction to Biotechnology: The science, technology and medical applications; Copyright; Contents; List of Figures; List of Tables; Preface; About the Author; Chapter 1. Membranes; 1.1 . Membrane Lipids; 1.2 . Cholesterol; 1.3 . Membrane Proteins; Questions; Chapter 2. Proteins; 2.1 . Amino Acids; 2.1.1 . p K a ; 2.2 . Protein Structure; 2.2.1 . Primary Structure; 2.2.2 . Secondary Structure; 2.2.2.1 . Supersecondary Structure; 2.2.3 . Tertiary Structure; 2.2.4 . Quaternary Structure; 2.3 . The Hydrophobic Effect; 2.4 . A Return to Membranes.
2.4.1 . Protein Movement Within the Plasma Membrane2.4.2 . Restriction of Protein Movement Within the Plasma Membrane; 2.4.3 . Protein Isolation Often Involves Detergents; Questions; Related Reading; Chapter 3: Cellular Transport; 3.1 . Membrane Transporters; 3.1.1 . The Sodium/Glucose Symporter; 3.1.2 . Transporters That Control pH; 3.1.2.1 . Examples of Passive Transport to Control pH; 3.1.2.2 . Examples of Active Transport to Control pH: The Proton ATPases; 3.1.2.3 . Lysosomes; 3.1.3 . Another Active Transporter: The Sodium/Potassium ATPase.
3.1.4 . Transporters can be Coupled: The Sodium-Driven Calcium Exchanger3.1.5 . ABC Transporters; 3.1.6 . Hydrophilic Molecule Transport and Electrochemical Gradients; 3.1.6.1 . The Nernst Equation; 3.2 . Vesicular Transporters: Endocytosis; 3.2.1 . Phagocytosis; 3.2.2 . Pinocytosis; 3.2.3 . Endocytosis via Clathrin-Coated Pits; 3.3 . Receptor Fates; 3.3.1 . Receptor Recycling: The LDL Receptor; 3.3.2 . Receptor and Ligand Recycling: The Transferrin Receptor; 3.3.3 . Neither Receptor nor Ligand are Recycled: The Opioid Receptor; 3.3.4 . Transcytosis.
3.4 . Lysosomes Are for Degradation, But Are They Safe?3.4.1 . Identification of Intracellular Vesicles; Questions; Related Reading; Chapter 4. Genes: The Blueprints for Proteins; 4.1 . Nucleotides and Nucleic Acids; 4.1.1 . The Phosphoribose Backbone; 4.1.2 . Nucleotide Bases, Nucleosides, and Nucleotides; 4.1.3 . DNA Is the Genetic Material; 4.1.4 . Genomic DNA Is Double-stranded; 4.1.5 . DNA Replication Is Semiconservative; 4.2 . From Genes to Proteins; 4.2.1 . Introduction to the Genetic Code; 4.2.1.1 . Degeneracy and Wobble; 4.2.1.1.1 . Ribosomes and Translation.
4.2.1.1.2 . Back to Wobble4.2.1.2 . Mutations and Their Effect on Translation; 4.2.2 . Genes; 4.2.2.1 . How Many Genes Are in the Human Genome?; 4.2.2.2 . Phenotypes; 4.2.3 . Transcription; 4.2.3.1 . The Start of Transcription: RNA Polymerase Binds to DNA; 4.2.3.1.1 . Prokaryotes; 4.2.3.1.2 . Eukaryotes; 4.2.3.1.2.1 . The Eukaryotic 5 2 mRNA Cap; 4.2.3.1.2.2 . Splicing; 4.2.3.1.2.3 . The Eukaryotic Poly(A) Tail; 4.2.3.2 . Regulation of Transcription; 4.2.3.2.1 . Promoters and Promoter Elements; 4.2.3.2.1.1 . TATA Box; 4.2.3.2.1.2 . CpG Islands; 4.2.3.2.1.3 . GC Box; 4.2.3.2.1.4 . CAAT Box.
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