Includes bibliographical references and index.

Online resource, title from PDF title page (EBSCO, viewed October 24, 2016).

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics-among other disciplines-that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology.

Part I. Designing vaccines from a new starting point : Broadly neutralizing antibodies / L. Morris and T.A. Moody -- part II. Pathogen free vaccines : Replication-competent viral vectors for vaccines delivery / C.L. Parks ; Reverse vaccinology: exploiting genomes for vaccines design / E. Del Tordello, R. Rappuoli and I. Delany ; Virus-like particle and nanoparticle vaccines / M. Kanekiyo and C.B. Buck -- part III. Immune monitoring : Systems vaccinology / M. Rolland and M.A. Eller ; Immunogenetics and vaccination / M. John, S. Gaudieri and S. Mallal -- part IV. Advanced vaccine development : Methodical considerations / P.B. Gilbert and R. Gottardo ; Vaccine development in special populations / K.M. Edwards and C.B. Creech.