Studies in natural products chemistry : Vol. 51 / [electronic resource]
by Rahman, Atta-ur- [editor.].
Material type: BookSeries: Studies in natural products chemistry: 51.Publisher: Amsterdam, Netherlands : Elsevier, 2016.Description: 1 online resource (xvi, 535 pages).ISBN: 9780444639387; 0444639381.Subject(s): Bioorganic chemistry | Bioactive compounds | Natural products | SCIENCE / Life Sciences / Biochemistry | Bioorganic chemistry | Bioactive compounds | Natural products | Electronic books | Electronic booksOnline resources: ScienceDirectIncludes index.
Includes bibliographical references and index.
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
Print version record.
Front Cover; Studies in Natural Products Chemistry; Studies in Natural Products Chemistry; Copyright; Contents; Contributors; Preface; 1 -- Potentially Chemopreventive Triterpenoids and Other Secondary Metabolites From Plants and Fungi; INTRODUCTION; EBV-EA INDUCTION TEST; TWO-STAGE CARCINOGENESIS TEST ON MOUSE SKIN; DMBA/TPA-Induced Carcinogenesis Test; PN/TPA-Induced Carcinogenesis Test; UVB/TPA-Induced Carcinogenesis Test; PLANT AND FUNGAL MATERIALS INVESTIGATED; INHIBITORY EFFECTS ON TPA-INDUCED EBV-EA ACTIVATION; INHIBITORY EFFECTS ON MOUSE SKIN CARCINOGENESIS
CHEMOPREVENTIVE EFFECTS OF TRITERPENOIDSCucurbitane-Type Triterpenoids; Cycloartane-Type Triterpenoids; Dammarane-Type Triterpenoids; Euphane-Type Triterpenoids; Lanostane-Type Triterpenoids; Limonoids; Lupane-Type Triterpenoids; Multiflorane-Type Triterpenoids; Oleanane-Type Triterpenoids; Taraxastane-Type Triterpenoids; Tirucallane-Type Triterpenoids; Ursane-Type Triterpenoids; CHEMOPREVENTIVE EFFECTS OF DITERPENOIDS; CHEMOPREVENTIVE EFFECTS OF STEROIDS; CHEMOPREVENTIVE EFFECTS OF CHALCONES; CHEMOPREVENTIVE EFFECTS OF FLAVONOIDS; CHEMOPREVENTIVE EFFECTS OF PHLOROGLUCINOLS
CHEMOPREVENTIVE EFFECTS OF OTHER SECONDARY METABOLIC COMPOUNDSPhenolic Compounds; Alkylresorcinols; Azaphilonoids; Caffeoylquinic Acids; Coumarins; Diarylheptanoids; Jasmonic Acid Derivatives; Tannins; CHEMOPREVENTIVE EFFECTS OF FATTY ACIDS; TOXICITY, SIDE EFFECTS, AND IMPROVEMENT OF BIOAVAILABILITY OF TRITERPENOIDS; Toxicity and Side Effects; Reciprocal Effect to Another Agent; Improvement of Bioavailability; Type of Preventive Malignancy by Triterpenoids; POTENTIAL MECHANISMS OF CHEMOPREVENTION; CONCLUDING REMARKS; ABBREVIATIONS; REFERENCES
2 -- Structural Diversity, Natural Sources and Pharmacological Potential of Naturally Occurring A-Seco-TriterpenoidsINTRODUCTION; ISOLATION AND STRUCTURE ELUCIDATION; SECO-TRITERPENOIDS AS BIOMARKERS; BIOSYNTHESIS; BIOLOGICAL ACTIVITY; ANTITUMOR ACTIVITY; EFFECTS OF A-SECO-TRITERPENOIDS ON THE IMMUNE SYSTEM; ANTIVIRAL ACTIVITY; ANTIBACTERIAL ACTIVITY; OTHER TYPES OF BIOLOGICAL ACTIVITY; THE MAIN APPROACHES TO SYNTHESIS OF A-SECO-TRITERPENOIDS; CONCLUSION; A-SECO-LANOSTANE TRITERPENOIDS; A-SECO-CYCLOARTANE TRITERPENOIDS; A-SECO-DAMMARANE TRITERPENOIDS; A-SECO-TIRUCALLANE TRITERPENOIDS
SCHISANDRA NORTRITERPENOIDSOTHER TETRACYCLIC A-SECO-TRITERPENOIDS; A-SECO-OLEANANE TRITERPENOIDS; A-SECO-URSANE TRITERPENOIDS; A-SECO-FRIEDELANE TRITERPENOIDS; A-SECO-LUPANE TRITERPENOIDS; OTHER PENTACYCLIC A-SECO-TRITERPENOIDS; OTHER A-SECO-TRITERPENOIDS; ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES; 3 -- Kaurenoic Acid: A Diterpene With a Wide Range of Biological Activities; INTRODUCTION; BIOSYNTHESIS OF KAURENOIC ACID; PHARMACOLOGICAL EFFECTS OF KAURENOIC ACID; Antidiabetic Activity; Smooth Muscle Relaxant Effect; Analgesic and Anti-inflammatory Properties; Diuretic and Antioxidant Activities
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