Applied biopharmaceutics & pharmacokinetics /
by Shargel, Leon; Yu, Andrew B. C; Wu-Pong, Susanna.
Material type:
BookPublisher: New York : McGraw-Hill, 2012Edition: 6th ed.Description: xi, 811 p. : 22 cm. ill.ISBN: 9780071603935 (hardcover : alk. paper); 007160393X (hardcover : alk. paper).Other title: Applied biopharmaceutics and pharmacokinetics.Subject(s): Biopharmaceutics | Pharmacokinetics | Biopharmaceutics | Models, Chemical | Pharmacokinetics| Item type | Current location | Collection | Call number | Copy number | Status | Date due | Barcode |
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Books
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Dhaka University Science Library General Stacks | Non Fiction | 615.7 SHA (Browse shelf) | Available | |||
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Books
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Dhaka University Science Library General Stacks | Non Fiction | 615.7 SHA (Browse shelf) | 1 | Available | 479262 |
Includes bibliographical references and index.
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
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