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A textbook of drug design and development /

by Krogsgaard-Larsen, Povl; Bundgaard, Hans.
Material type: materialTypeLabelBookPublisher: Australia : Harwood Academic Publishers, c1996Edition: 2nd ed.Description: [viii], 543 p. : ill. (some col.) ; 26 cm.ISBN: 3718658666 (hardcover); 3718658674 (softcover).Subject(s): Drugs -- Design | Drug Design
Contents:
Drug Discovery: An Overview / Michael Williams and Eric M. Gordon -- Structural and Physicochemical Factors in Drug Action / Uli Hacksell -- Computer-aided Development of Three-dimensional Pharmacophore Models / Tommy Liljefors and Ingrid Pettersson -- Quantitative Structure-activity Relationships and Experimental Design / Thomas Hogberg and Ulf Norinder -- Gene Technology in Pharmaceutical Research and Production / Nanni Din, Jens G. L. Petersen, Henrik Dalboge and Soren Carlsen -- Receptors / Claus Braestrup -- Radiotracers: Synthesis and Use in Imaging / Christer Halldin and Thomas Hogberg -- Ion Channels / David J. Triggle -- Excitatory Amino Acid Receptors / Ulf Madsen -- Synaptic Mechanisms as Pharmacological Targets: Gaba, Acetylcholine and Histamine / Povl Krogsgaard-Larsen and Bente Frolund -- Enzymes and Enzyme Inhibitors / Ian Ahnfelt-Ronne --
Bio-inorganic Chemistry / Ole Jons and Erik Sylvest Johansen -- Design and Application of Prodrugs / Gitte Juel Friis and Hans Bundgaard -- Peptides and Peptidomimetics / Kristina Luthman and Uli Hacksell -- Bioactive Ether-linked Phospholipids: Platelet-activating Factor (PAF) and Analogs / Fred Snyder -- Classical Antiviral Agents and Design of New Antiviral Agents / Piet Herdewijn and Erik de Clercq -- Anticancer Agents / Ingrid Kjoller Larsen -- Drug Development: From Discovery to Marketing / Joseph P. Yevich.
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General Stacks 		Non Fiction TEX (Browse shelf) 2 Available 389050

Includes bibliographical references and index.

Ch. 1. Drug Discovery: An Overview / Michael Williams and Eric M. Gordon -- Ch. 2. Structural and Physicochemical Factors in Drug Action / Uli Hacksell -- Ch. 3. Computer-aided Development of Three-dimensional Pharmacophore Models / Tommy Liljefors and Ingrid Pettersson -- Ch. 4. Quantitative Structure-activity Relationships and Experimental Design / Thomas Hogberg and Ulf Norinder -- Ch. 5. Gene Technology in Pharmaceutical Research and Production / Nanni Din, Jens G. L. Petersen, Henrik Dalboge and Soren Carlsen -- Ch. 6. Receptors / Claus Braestrup -- Ch. 7. Radiotracers: Synthesis and Use in Imaging / Christer Halldin and Thomas Hogberg -- Ch. 8. Ion Channels / David J. Triggle -- Ch. 9. Excitatory Amino Acid Receptors / Ulf Madsen -- Ch. 10. Synaptic Mechanisms as Pharmacological Targets: Gaba, Acetylcholine and Histamine / Povl Krogsgaard-Larsen and Bente Frolund -- Ch. 11. Enzymes and Enzyme Inhibitors / Ian Ahnfelt-Ronne --

Ch. 12. Bio-inorganic Chemistry / Ole Jons and Erik Sylvest Johansen -- Ch. 13. Design and Application of Prodrugs / Gitte Juel Friis and Hans Bundgaard -- Ch. 14. Peptides and Peptidomimetics / Kristina Luthman and Uli Hacksell -- Ch. 15. Bioactive Ether-linked Phospholipids: Platelet-activating Factor (PAF) and Analogs / Fred Snyder -- Ch. 16. Classical Antiviral Agents and Design of New Antiviral Agents / Piet Herdewijn and Erik de Clercq -- Ch. 17. Anticancer Agents / Ingrid Kjoller Larsen -- Ch. 18. Drug Development: From Discovery to Marketing / Joseph P. Yevich.

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