Includes bibliographical references and index.

Elements for the development of strategies for compound library enhancement / Edgar Jacoby -- The European lead factory / Christopher Kallus, Jörg Hüser, Philip S. Jones, Adam Nelson -- Access to compound collections : new business models for compound acquisition and sharing / Peter ten Holte -- New advances in diversity-oriented synthesis / Warren R.J.D. Galloway, Jamie E. Stokes, David R. Spring -- Solid-phase combinatorial chemistry : ready for a revival? / Marcel Patek, Martin Smrcina, Eric Wegrzyniak, Victor Nikolaev, Andres Mariscal -- Recent advances in multicomponent reaction chemistry : applications in small molecule drug discovery / Christopher Hulme, Muhammad Ayaz, Guillermo Martinez-Ariza, Federico Medda, Arthur Shaw -- Computational techniques to support hit triage / Douglas B. Kitchen, Hélène Y. Decornez -- Fragment-based drug discovery / Jean-Paul Renaud, Thomas Neumann and Luc Van Hijfte -- Virtual screening / Karl-Heinz Baringhaus, Gerhard Hessler -- Phenotypic screening / Michelle Palmer -- Advances in the understanding of drug properties in medicinal chemistry / Peter Hamley, Patrick Jimonet -- Recent developments in automated solution phase library production / Thomas C. Maier, Werngard Czechtizky -- Adme profiling : an introduction for the medicinal chemist / Katharina Mertsch, Martin Will, Werngard Czechtizky, Niels Griesang, Alexander Marker, Jacob Olsen -- The role of natural products in drug discovery : examples of marketed drugs / Lars Ole Haustedt and Karsten Siems -- Peptidomimetics of a-helical and b-strand protein binding epitopes / Nina Bionda, Rudi Fasan -- In vivo imaging of drug action / Oliver Plettenburg, Matthias Löhn.

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