Ligand design in medicinal inorganic chemistry / [electronic resource]
by Storr, Tim [editor.].
Material type:
BookPublisher: Chichester, West Sussex : John Wiley & Sons Inc., 2014.Description: 1 online resource.ISBN: 9781118697894; 1118697898; 9781118697917; 111869791X; 9781118697191; 1118697197; 1118488520; 9781118488522.Subject(s): DNA-drug interactions | Ligand binding (Biochemistry) | Drugs -- Design | Pharmaceutical chemistry | ADN | Medicaments -- Disseny | Lligands (Bioquímica) | Química farmacèutica | MEDICAL -- Physiology | SCIENCE -- Life Sciences -- Human Anatomy & Physiology | DNA-drug interactions | Drugs -- Design | Ligand binding (Biochemistry) | Pharmaceutical chemistry | Llibres electrònics | Electronic books | Electronic booksOnline resources: Wiley Online Library Includes bibliographical references and index.
Introduction to ligand design in medicinal inorganic chemistry -- Platinum-based anticancer agents -- Coordination chemistry and ligand design in the development of metal based radiopharmaceuticals -- Ligand design in D-block optical imaging agents and sensors -- Luminescent lanthanoid probes -- Metal complexes of carbohydrate-targeted ligands in medicinal inorganic chemistry -- Design of Schiff base-derived ligands: applications in therapeutics and medical diagnosis -- Metal-based antimalarial agents -- Therapeutic gold compounds -- Ligand design to target and modulate metal-protein interactions in neurodegenerative diseases -- Rational design of copper and iron chelators to treat Wilson's disease and hemochromatosis -- MRI contrast agents -- Photoactivatable metal complexes and their use in biology and medicine -- Metalloprotein inhibitors -- Ruthenium anticancer compounds with biologically-derived ligands.
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