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001 10818114
003 BD-DhUL
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006 m d
007 cr n
008 140601s2014 nyua s |||1 0|eng
020 _a9781493907151
020 _a9781493907144 (print)
020 _a9781493907144
024 7 _a10.1007/978-1-4939-0715-1
_2doi
035 _a(WaSeSS)ssj0001199639
040 _dWaSeSS
_dBD-DhUL
_cBD-DhUL
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
072 7 _aSCI064000
_2bisacsh
082 0 4 _a570
_223
_bELN
100 1 _aEl-Metwally, Sara.
245 1 0 _aNext generation sequencing technologies and challenges in sequence assembly
_cSara El-Metwally, Osama M. Ouda, Mohamed Helmy.
264 1 _aNew York :
_bSpringer,
_c2014.
300 _axii, 118 p. :
_bill. ;
_c23 cm.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
365 _aEuro
_b15.99
490 0 _aSpringer briefs in systems biology
504 _aIncludes bibliographical references
506 _aLicense restrictions may limit access.
520 _aThe introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
650 0 _aLife sciences.
650 0 _aHuman genetics.
650 0 _aBioinformatics.
650 0 _aBiological models.
650 1 4 _aLife Sciences.
650 2 4 _aSystems Biology.
650 2 4 _aHuman Genetics.
650 2 4 _aBioinformatics.
700 1 _aOuda, Osama M.
_eauthor.
700 1 _aHelmy, Mohamed.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
773 0 _tSpringerLINK ebooks - Biomedical and Life Sciences (2014)
773 0 _tSpringerLINK Tracts in Modern Physics
776 0 8 _iPrinted edition:
_z9781493907144
830 0 _aSpringerBriefs in Systems Biology,
_x2193-4746 ;
_v7
856 4 0 _uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio10818114.001
_zFull text available from SpringerLINK ebooks - Biomedical and Life Sciences (2014)
856 4 0 _uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio10818114.002
_zFull text available from SpringerLINK Tracts in Modern Physics
942 _2ddc
_cBK
999 _c105898
_d105898