000 | 03331cam a2200733Ii 4500 | ||
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001 | ocn805654697 | ||
003 | OCoLC | ||
005 | 20171114084244.0 | ||
006 | m o d | ||
007 | cr ||||||||||| | ||
008 | 120809t20122012gw a ob 001 0 eng d | ||
020 | _a9783527645640 | ||
020 | _a3527645640 | ||
020 | _a9783527645664 | ||
020 | _a3527645667 | ||
020 | _z9783527332267 | ||
020 | _z352733226X | ||
020 | _z9783527645657 | ||
020 | _z3527645659 | ||
020 | _z9783527645671 | ||
020 | _z3527645675 | ||
020 | _z9781283893244 | ||
020 | _z128389324X | ||
029 | 1 |
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035 |
_a(OCoLC)805654697 _z(OCoLC)961515877 _z(OCoLC)962633579 _z(OCoLC)966211547 |
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040 |
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049 | _aMAIN | ||
050 | 4 | _aRS403 | |
072 | 7 |
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082 | 0 | 4 | _a615.19 |
100 | 1 | _aDörwald, Florencio Zaragoza. | |
245 | 1 | 0 |
_aLead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds / _cFlorencioa Zaragoza Dörwald. _h[electronic resource] |
264 | 1 |
_aWeinheim : _bWiley-VCH Verlag GmBH & Co., _c[2012] |
|
264 | 4 | _c©2012 | |
300 |
_a1 online resource (xvi, 605 pages) : _billustrations |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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380 | _aBibliography | ||
504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _apt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes. | |
520 | _aSmall structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy. | ||
588 | 0 | _aOnline resource; title from home page (viewed May 23, 2014). | |
650 | 0 | _aPharmaceutical chemistry. | |
650 | 7 |
_aMEDICAL _xDrug Guides. _2bisacsh |
|
650 | 7 |
_aMEDICAL _xNursing _xPharmacology. _2bisacsh |
|
650 | 7 |
_aMEDICAL _xPharmacology. _2bisacsh |
|
650 | 7 |
_aMEDICAL _xPharmacy. _2bisacsh |
|
650 | 7 |
_aPharmaceutical chemistry. _2fast _0(OCoLC)fst01060115 |
|
655 | 4 | _aElectronic books. | |
655 | 7 |
_aElectronic books. _2local |
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776 | 0 | 8 |
_iPrint version: _aDörwald, Florencio Zaragoza. _tLead optimization for medicinal chemists. _dWeinheim : Wiley-VCH, ©2012 _z9783527332267 _w(OCoLC)793414338 |
856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9783527645640 _zWiley Online Library |
942 |
_2ddc _cBK |
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999 |
_c206101 _d206101 |