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006 m o d
007 cr |||||||||||
008 120809t20122012gw a ob 001 0 eng d
020 _a9783527645640
020 _a3527645640
020 _a9783527645664
020 _a3527645667
020 _z9783527332267
020 _z352733226X
020 _z9783527645657
020 _z3527645659
020 _z9783527645671
020 _z3527645675
020 _z9781283893244
020 _z128389324X
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035 _a(OCoLC)805654697
_z(OCoLC)961515877
_z(OCoLC)962633579
_z(OCoLC)966211547
040 _aYDXCP
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082 0 4 _a615.19
100 1 _aDörwald, Florencio Zaragoza.
245 1 0 _aLead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds /
_cFlorencioa Zaragoza Dörwald.
_h[electronic resource]
264 1 _aWeinheim :
_bWiley-VCH Verlag GmBH & Co.,
_c[2012]
264 4 _c©2012
300 _a1 online resource (xvi, 605 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
380 _aBibliography
504 _aIncludes bibliographical references and index.
505 0 _apt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.
520 _aSmall structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.
588 0 _aOnline resource; title from home page (viewed May 23, 2014).
650 0 _aPharmaceutical chemistry.
650 7 _aMEDICAL
_xDrug Guides.
_2bisacsh
650 7 _aMEDICAL
_xNursing
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
650 7 _aPharmaceutical chemistry.
_2fast
_0(OCoLC)fst01060115
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
776 0 8 _iPrint version:
_aDörwald, Florencio Zaragoza.
_tLead optimization for medicinal chemists.
_dWeinheim : Wiley-VCH, ©2012
_z9783527332267
_w(OCoLC)793414338
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527645640
_zWiley Online Library
942 _2ddc
_cBK
999 _c206101
_d206101