000 | 04742cam a2200769Ii 4500 | ||
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001 | ocn809370453 | ||
003 | OCoLC | ||
005 | 20171114083050.0 | ||
006 | m o d | ||
007 | cr ||||||||||| | ||
008 | 120907t20122012njua ob 001 0 eng | ||
010 | _z 2012012322 | ||
020 |
_a9781118437674 _q(electronic bk.) |
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020 |
_a1118437675 _q(electronic bk.) |
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020 |
_a9781118435762 _q(electronic bk.) |
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020 |
_a1118435761 _q(electronic bk.) |
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020 |
_a9781118434505 _q(electronic bk.) |
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020 |
_a1118434501 _q(electronic bk.) |
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020 | _z9781118101186 | ||
020 | _z1118101189 | ||
020 | _z9781283576055 | ||
020 | _z1283576058 | ||
029 | 1 |
_aAU@ _b000050060747 |
|
029 | 1 |
_aAU@ _b000051432790 |
|
029 | 1 |
_aDEBBG _bBV041121688 |
|
029 | 1 |
_aDEBBG _bBV041829088 |
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029 | 1 |
_aDEBSZ _b396766102 |
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029 | 1 |
_aDEBSZ _b431131015 |
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029 | 1 |
_aDKDLA _b820120-katalog:000600184 |
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029 | 1 |
_aNZ1 _b14976643 |
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_aAU@ _b000059228019 |
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035 |
_a(OCoLC)809370453 _z(OCoLC)808771990 _z(OCoLC)811488646 _z(OCoLC)841331222 _z(OCoLC)961537416 _z(OCoLC)962595044 _z(OCoLC)966148373 |
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037 |
_aCL0500000213 _bSafari Books Online |
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037 |
_aFB5E82B8-484A-4B92-BA65-C660A94D88E7 _bOverDrive, Inc. _nhttp://www.overdrive.com |
||
040 |
_aDG1 _beng _erda _epn _cDG1 _dOCLCQ _dN$T _dYDXCP _dE7B _dOCLCQ _dCDX _dOCLCQ _dCCO _dMHW _dUMI _dOCLCO _dCOO _dDEBSZ _dTEFOD _dOCLCQ _dOCLCF _dOCLCQ _dMMU _dTEFOD _dEBLCP _dOCLCQ _dAZK _dDG1 _dOCLCO _dLOA _dOCLCA |
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049 | _aMAIN | ||
050 | 4 | _aQP514.2 | |
060 | 4 | _aQV 745 | |
072 | 7 |
_aSCI _x007000 _2bisacsh |
|
082 | 0 | 4 |
_a572 _223 |
245 | 0 | 0 |
_aChemical biology : approaches to drug discovery and development to targeting disease / _cedited by Natanya Civjan. _h[electronic resource] |
264 | 1 |
_aHoboken, N.J. : _bWiley, a John Wiley & Sons, Inc., Publication, _c[2012] |
|
264 | 4 | _c©2013 | |
300 |
_a1 online resource (525 pages) : _billustrations |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_adata file _2rda |
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380 | _aBibliography | ||
504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _aPart I: Drug discovery and development. The role of chemical biology in drug discovery -- Computational approaches to drug discovery and development -- Design and selection of small molecule inhibitors -- Lead optimization in drug discovery -- Pharmacokinetics of drug candidates -- ADME properties of drugs -- Drug transport in living systems -- Blood-brain barrier: considerations in drug development and delivery -- Pharmacokinetic considerations: methods and systems of controlled drug delivery -- Pharmaceuticals: natural products and natural product models -- Part II: Chemical biology to understand and target disease. The role of chemical biology in understanding and treating disease: are small molecule "correctors" the way of the future? -- Anxiety disorders -- Chronic obstructive pulmonary disease (COPD) -- Depression -- Osteoarthritis -- Human immunodeficiency virus (HIV) -- Allergy and asthma -- Schizophrenia -- Protein misfolding and disease -- Protein trafficking diseases -- Metabolic diseases -- Mitochondrial medicine -- Lysosomal disorders. | |
520 | _a"Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease"--Provided by publisher. | ||
588 | 0 | _aOnline resource; title from electronic title page (ebrary, viewed on February 24, 2015). | |
650 | 0 | _aBiochemistry. | |
650 | 1 | 2 | _aDrug Discovery. |
650 | 2 | 2 | _aDrug Delivery Systems. |
650 | 4 | _aBiochemistry. | |
650 | 7 |
_aSCIENCE _xLife Sciences _xBiochemistry. _2bisacsh |
|
650 | 7 |
_aBiochemistry. _2fast _0(OCoLC)fst00831961 |
|
650 | 7 |
_aBiochemistry. _2local |
|
655 | 4 | _aElectronic books. | |
655 | 7 |
_aElectronic books. _2local |
|
700 | 1 |
_aCivjan, Natanya, _eeditor. |
|
776 | 0 | 8 |
_iPrint version: _tChemical biology. _dHoboken, N.J. : Wiley, 2012 _z9781118101186 _w(DLC) 2012012322 _w(OCoLC)749857596 |
856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9781118435762 _zWiley Online Library |
942 |
_2ddc _cBK |
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999 |
_c206148 _d206148 |