000 05216cam a2200757Ka 4500
001 ocn809920135
003 OCoLC
005 20171113140926.0
006 m o d
007 cr cn|||||||||
008 120914s2012 gw fob 001 0 eng d
020 _a9783527630905
_q(electronic bk.)
020 _a3527630902
_q(electronic bk.)
020 _a9783527329038
_q(Cloth)
020 _a352732903X
_q(Cloth)
020 _a9783527630912
_q(ePDF)
020 _a3527630910
_q(ePDF)
020 _a9783527646326
_q(ePub)
020 _a3527646329
_q(ePub)
020 _a9783527646333
_q(mobi)
020 _a3527646337
_q(mobi)
020 _a9781280665653
_q(MyiLibrary)
020 _a1280665653
_q(MyiLibrary)
024 8 _a9786613642585
029 1 _aDEBBG
_bBV041048631
029 1 _aDKDLA
_b820120-katalog:000600786
029 1 _aNZ1
_b15121289
035 _a(OCoLC)809920135
_z(OCoLC)794620384
_z(OCoLC)823842515
037 _a10.1002/9783527630905
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
040 _aDG1
_beng
_epn
_cDG1
_dOCLCO
_dCDX
_dOKU
_dOCLCQ
_dOCLCF
_dOCLCA
_dUV0
_dCOO
_dDKDLA
_dDEBBG
_dYDXCP
_dOCLCO
_dOCLCQ
_dOCLCO
_dOCLCQ
049 _aMAIN
050 4 _aRA1211
060 4 _aQV 600
072 7 _aHEA
_2eflch
082 0 4 _a615.9
_223
245 0 0 _aMetabolism of drugs and other xenobiotics /
_cedited by Pavel Anzenbacher, Ulrich M. Zanger.
_h[electronic resource]
260 _aWeinheim :
_bWiley-VCH,
_c2012.
300 _a1 online resource (734 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aFront Matter -- Biochemistry and Molecular Genetics of Drug Metabolism. Drug-Metabolizing Enzymes₆An Overview / Pavel Anzenbacher, Eva Anzenbacherov̀ -- Cytochromes P450 / F Peter Guengerich -- UDP-Glucuronosyltransferases / Christian P Strassburg, Sandra Kalthoff -- Sulfotransferases / Michael W H Coughtrie -- Glutathione -Transferases / Miroslav Dostalek, Anna-Katarina Stark -- Hydrolytic Enzymes / Bingfang Yan -- Transporting Systems / Anne T Nies, Claudia Resch, Tadashi Namisaki -- Transcriptional Regulation of Human Drug-Metabolizing Cytochrome P450 Enzymes / Zdenek Dvorak -- Importance of Pharmacogenomics / Ulrich M Zanger, Kathrin Klein, Jessica Rieger -- Metabolism of Drugs. Introduction to Drug Metabolism / Ulrich M Zanger -- Central Nervous System Drugs / Pierre Baumann, Christoph Hiemke -- Cardiovascular Drugs / Stephan Riedmaier, Ulrich M Zanger -- Anticancer Drugs / Matthias Schwab, Elke Schaeffeler, Hiltrud Brauch -- Antimicrobial Agents / Chantal Csajka, Oscar Marchetti, Oriol Manuel, Laurent Decosterd, Amalio Telenti -- Drugs against Acute and Chronic Pain / Andrew A Somogyi, Janet K Coller -- Drugs of Abuse (Including Designer Drugs) / Markus R Meyer, Hans H Maurer -- Nicotine Metabolism and its Implications / Andy Z X Zhu, Rachel F Tyndale -- Metabolism of Alcohol and its Consequences / Helmut K Seitz, Sebastian Mueller -- Metabolism of Natural Compounds. Introduction and Overview / Michael Murray -- Flavonoids / Petr Hodek -- St John's Wort (L.) / Miroslav Dostalek, Anna-Katarina Stark -- Food Components and Supplements / Alexandr Parlesak -- Metabolism of Unnatural Xenobiotics. Environmental Pollutants / Marie Stiborova -- Environmental Estrogens / Miroslav Machala, Jan Vondr̀cek -- Biotransformation of Insecticides / Corie A Ellison, Alice L Crane, James R Olson -- Index.
520 _aA practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this.
588 0 _aPrint version record.
650 0 _aXenobiotics
_xMetabolism.
650 0 _aBiotransformation (Metabolism)
650 0 _aToxicology.
650 1 2 _aBiotransformation
_xphysiology.
650 1 2 _aXenobiotics
_xmetabolism.
650 2 2 _aBiological Agents
_xmetabolism.
650 2 2 _aEnvironmental Pollutants
_xmetabolism.
650 2 2 _aPharmaceutical Preparations
_xmetabolism.
650 2 2 _aPharmacokinetics.
650 2 2 _aToxicology.
650 7 _aBiotransformation (Metabolism)
_2fast
_0(OCoLC)fst00832858
650 7 _aToxicology.
_2fast
_0(OCoLC)fst01153364
650 7 _aXenobiotics
_xMetabolism.
_2fast
_0(OCoLC)fst01181975
655 4 _aElectronic books.
700 1 _aAnzenbacher, Pavel.
700 1 _aZanger, Ulrich M.,
_d1955-
710 2 _aWiley InterScience (Online service)
776 0 8 _iPrint version:
_tMetabolism of drugs and other xenobiotics.
_dWeinheim : Wiley-VCH, 2012
_z9783527329038
_w(OCoLC)794620384
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527630905
_zWiley Online Library
942 _2ddc
_cBK
999 _c206164
_d206164