000			04899cam a2200697Ii 4500
001			ocn857365390
003			OCoLC
005			20171106090201.0
006			m o d
007			cr |||||||||||
008			130831t20132014gw af ob 001 0 eng d
020			_a9783527665785 _q(electronic bk.)
020			_a3527665781 _q(electronic bk.)
020			_a9783527665815 _q(electronic bk.)
020			_a3527665811 _q(electronic bk.)
020			_a9783527665808 _q(ePub)
020			_a3527665803 _q(ePub)
020			_a9783527665792 _q(Mobi)
020			_a352766579X _q(Mobi)
020			_a9781299830240 _q(MyiLibrary)
020			_a1299830242 _q(MyiLibrary)
020			_z9783527333875
020			_z3527333878 _q(hbk.)
020			_z9783527333875 _q(hbk.)
029	1		_aAU@ _b000052185307
029	1		_aCHBIS _b010131681
029	1		_aCHVBK _b314710647
029	1		_aDEBSZ _b431491003
029	1		_aNZ1 _b15340131
035			_a(OCoLC)857365390 _z(OCoLC)861745523 _z(OCoLC)867190737 _z(OCoLC)898613211 _z(OCoLC)915719420 _z(OCoLC)960202377 _z(OCoLC)961667848 _z(OCoLC)962584475
037			_a514275 _bMIL
040			_aEBLCP _beng _erda _epn _cEBLCP _dIDEBK _dCUS _dMHW _dDG1 _dN$T _dCOO _dYDXCP _dIUL _dCDX _dOCLCO _dRECBK _dMEU _dN15 _dOCLCF _dDEBSZ _dOCLCO _dOCLCQ _dOCLCO _dLOA _dOCLCO _dOCLCQ _dOCLCO
049			_aMAIN
050		4	_aQD461
072		7	_aSCI _x016000 _2bisacsh
082	0	4	_a548.478
245	0	0	_aSynthetic methods for biologically active molecules : exploring the potential of bioreductions / _cedited by Elisabetta Brenna. _h[electronic resource]
264		1	_aWeinheim, Germany : _bWiley-VCH, _c2013.
264		4	_c©2014
300			_a1 online resource (xviii, 387 pages) : _billustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0		_aDevelopment of Sustainable Biocatalytic Reduction Processes for Organic Chemists / Roland Wohlgemuth -- Reductases: From Natural Diversity to Established Biocatalysis and to Emerging Enzymatic Activities / Elena Fernández-Álvaro, Pablo Domínguez de María -- Synthetic Strategies Based on C=C Bioreductions for the Preparation of Biologically Active Molecules / Francesco G Gatti, Fabio Parmeggiani, Alessandro Sacchetti -- Synthetic Strategies Based on C=O Bioreductions for the Preparation of Biologically Active Molecules / Aníbal Cuetos, Alba Díaz-Rodríguez, Iván Lavandera -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=C Double Bonds / Sabrina Kille, Manfred T Reetz -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=O Double Bonds / Nobuya Itoh, Yoshihide Makino -- Synthetic Applications of Aminotransferases for the Preparation of Biologically Active Molecules / Sachin Pannuri, Sanjay Kamat, Abraham R Mártin-García -- Strategies for Cofactor Regeneration in Biocatalyzed Reductions / Selin Kara, Joerg H Schrittwieser, Frank Hollmann -- Solvent Effects in Bioreductions / Yan Ni, Hui-Lei Yu, Jian-He Xu -- Application of Product Removal (ISPR) Technologies for Implementation and Scale-Up of Biocatalytic Reductions / John M Woodley -- Bioreductions in Multienzymatic One-Pot and Cascade Processes / Daniela Monti, Erica E Ferrandi -- Dynamic Kinetic Resolutions Based on Reduction Processes / Dimitris Kalaitzakis, Ioulia Smonou -- Relevant Practical Applications of Bioreduction Processes in the Synthesis of Active Pharmaceutical Ingredients / Gábor Tasnádi, Mélanie Hall.
520			_aThis ready reference focuses on the currently available toolbox of biocatalysed reductions of C=O, C=C and formal C=N double bonds to show which transformations are reliable for use in manufacturing processes and which still require improvements and investigation. Following an introductory chapter, chapters 2-4 present the synthetic strategies which are currently available for the reduction of C=C, C=O and for reductive amination, by means of whole cell catalysts and isolated enzymes.
546			_aText in English.
588	0		_aOnline resource; title from PDF title page (Wiley, viewed September 24, 2013).
650		0	_aReduction (Chemistry)
650		0	_aBioactive compounds _xSynthesis.
650		0	_aEnzymes _xBiotechnology.
650		0	_aEnzymes _xIndustrial applications.
650		7	_aSCIENCE _xPhysics _xCrystallography. _2bisacsh
650		7	_aBiochemistry. _2fast _0(OCoLC)fst00831961
650		7	_aBiomolecules. _2fast _0(OCoLC)fst00832624
655		4	_aElectronic books.
700	1		_aBrenna, Elisabetta.
776	0	8	_iPrint version: _tSynthetic methods for biologically active molecules. _dWeinheim : Wiley-VCH, 2013 _z9783527333875 _w(OCoLC)856201927
856	4	0	_uhttp://onlinelibrary.wiley.com/book/10.1002/9783527665785 _zWiley Online Library
942			_2ddc _cBK
999			_c206968 _d206968