000 06451cam a2200685 i 4500
001 ocn862053174
003 OCoLC
005 20171105120818.0
006 m o d
007 cr |||||||||||
008 131101s2014 nju ob 001 0 eng
010 _a 2013043944
020 _a9781118444153 (ePub)
020 _a1118444159 (ePub)
020 _a9781118444092 (Adobe PDF)
020 _a1118444094 (Adobe PDF)
020 _z9781118444160 (cloth)
020 _a9781118444122
020 _a1118444124
020 _a1118444167
020 _a9781118444160
028 0 1 _aEB00257519
_bRecorded Books
029 1 _aCHBIS
_b010441985
029 1 _aCHVBK
_b334094003
029 1 _aDEBSZ
_b431634939
029 1 _aNZ1
_b15497375
029 1 _aNZ1
_b15906652
029 1 _aDEBBG
_bBV043396323
035 _a(OCoLC)862053174
_z(OCoLC)883262616
_z(OCoLC)960201521
_z(OCoLC)961625294
_z(OCoLC)962639604
040 _aDLC
_beng
_erda
_cDLC
_dYDX
_dEBLCP
_dN$T
_dDG1
_dE7B
_dCUI
_dYDXCP
_dCOO
_dOCLCF
_dNLGGC
_dDEBSZ
_dRECBK
_dOCLCO
_dDEBBG
_dLOA
042 _apcc
049 _aMAIN
050 0 0 _aQP552.W58
060 1 0 _aQU 55.2
072 7 _aSCI
_x007000
_2bisacsh
082 0 0 _a572/.64
_223
245 0 0 _aWnt signaling in development and disease : molecular mechanisms and biological functions /
_c[edited by] Stefan Hoppler, Randall T. Moon.
_h[electronic resource]
264 1 _aHoboken, New Jersey :
_bWiley Blackwell,
_c[2014]
300 _a1 online resource.
336 _atext
_2rdacontent
337 _acomputer
_2rdamedia
338 _aonline resource
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 8 _aMachine generated contents note: Part A: Molecular Signaling Mechanisms: from Pathways to Networks -- Chapter 1: Sending of the Wnt signal and its reception at the membrane (an overview) / Xi He, Rik Korswagen -- Chapter 2: Introduction to Wnt Signal transduction in the cytoplasm / Xi He -- Chapter 3: Regulation of gene expression by Wnt signaling in the nucleus (an overview) / Marian Waterman, Ken Cadigan -- Chapter 4: Wnt target genes: Insights from bioinformatics / Ken Cadigan -- Chapter 5: Introduction to [beta]-catenin-independent Wnt signaling pathways / Michael Kuhl, David Strutt -- Chapter 6: Choice and specificity of Wnt signaling pathways / Guido Zaman, Stuart Aaronson -- Chapter 7: The Cell Biology of Wnt signaling / John Wallingford, Kikuchi -- Chapter 8: New insights from proteomic analysis of Wnt signaling / Ben Major -- Chapter 9: New insights about Wnt pathway mechanisms from global siRNA screens / Ram Dasgupta -- Chapter 10: Insights from mathematical modeling on Wnt signaling network / M. Kuhl -- Chapter 11: The evolution of Wnt signaling / Jenifer Croce (David McClay), Thomas Holstein, Linda Holland -- Part B: Selected key molecules in Wnt signaling -- Chapter 12: The Wnt signal / Roel Nusse, Karl Willert -- Chapter 13: Secreted Wnt inhibitors or modulators / Herbert Steinbeisser, Robert Kypta, Masanori Taira, Paola Bovolenta and Javier Lopez-Rios -- Chapter 14: Frizzleds as G-Protein Coupled Receptors / Gunnar Schulte (Craig Malbon and Randall Moon) -- Chapter 15: Dishevelled, at the crossroads of pathways / Mariann Bienz, John Wallinford, Vitezslav Bryja -- Chapter 16: [beta]-catenin, jobs for one protein in signaling and cell adhesion / Jonathan Pettitt, Cara Gottardi, Koni Basler, Bienz -- Chapter 17: Variety of TCF/LEF structure and function in vertebrate Wnt signaling / Mariann Waterman, Hoppler, Bradley Merrill -- Chapter 18: Insights from Structural Analysis of protein-protein interactions by Wnt Pathway Components and functional multi-protein complex formation / Wenqing Xu -- Part C: Wnt Signaling in Embryonic Development and Adult Tissue Homeostasis -- Chapter 19: Wnt signaling in Early embryonic development: From Fertilization To Gastrulation (an introduction) / Stefan Hoppler -- Chapter 20: Wnt signaling in Embryonic Stem Cells: Insights into Early Mammalian Development / Kathy Davidson -- Chapter 21: Wnt signaling specifying Neural Lineages / Corinne Houart, Richard Dorsky -- Chapter 22: Wnt signaling in Heart Organogenesis / Morressey, Hoppler, M. Kuhl -- Chapter 23: Wnt signaling in Kidney organogenesis / Andy McMahon, Seppo Vainio -- Chapter 24: Wnt signaling regulation of tissue architecture (EMT and MET) and morphogenesis / Liz Vincan -- Chapter 25: Wnt Signaling in Tissue Homeostasis in Adults / Elaine Fuchs, Hans Clevers -- Chapter 26: Restoring Tissue Homeostasis: Wnt Signaling in Tissue Regeneration After Acute Injury / Author tbd -- PART D: Wnt Signaling In Chronic Disease -- Chapter 27: Wnt signaling in Disease (an overview) / Randall Moon -- Chapter 28: Wnt signaling in Colorectal Cancer / Paul Polakis or Riccardo Fodde, Owen Sansom -- Chapter 29: Wnt signaling in Melanoma / Andy Chien -- Chapter 30: Wnt signaling in psychiatric disease and dementia / Stephen Haggarty -- Chapter 31: Wnt signaling Therapeutics / Trevor Dale, Randall Moon, et al.
520 _a"Widely recognized as one of the most important signaling mechanisms in development and disease, Wnt signaling pathways are networks of proteins that play significant roles in embryogenesis or cancer development. Wnt Signaling in Development and Disease addresses the fundamentals of Wnt signaling and delves into molecular pathway mechanisms, its role in embryogenesis, adult tissue homeostasis, and chronic disease. This comprehensive resource details current knowledge of Wnt signaling while looking ahead to future progress"--Provided by publisher.
588 _aDescription based on print version record and CIP data provided by publisher.
650 2 _aWnt Proteins
_xphysiology.
650 0 _aWnt proteins.
650 0 _aCellular signal transduction.
650 7 _aSCIENCE
_xLife Sciences
_xBiochemistry.
_2bisacsh
650 7 _aCellular signal transduction.
_2fast
_0(OCoLC)fst00850288
650 7 _aWnt proteins.
_2fast
_0(OCoLC)fst01176458
655 4 _aElectronic books.
655 0 _aElectronic books.
700 1 _aHoppler, Stefan,
_d1965-
_eeditor of compilation.
700 1 _aMoon, Randall T.,
_eeditor of compilation.
776 0 8 _iPrint version:
_tWnt signaling in development and disease
_dHoboken, New Jersey : John Wiley & Sons, [2014]
_z9781118444160
_w(DLC) 2013042745
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9781118444122
_zWiley Online Library
942 _2ddc
_cBK
999 _c207067
_d207067