000			03683cam a2200721Ii 4500
001			ocn905991359
003			OCoLC
005			20171025084459.0
006			m o d
007			cr cnu---unuuu
008			150328s2015 gw ob 001 0 eng d
020			_a9783527673049 _qelectronic bk.
020			_a3527673040 _qelectronic bk.
020			_a9783527673025 _qelectronic bk.
020			_a3527673024 _qelectronic bk.
020			_z9783527673056 _qelectronic bk.
020			_z3527673059 _qelectronic bk.
020			_a9783527673032 _qelectronic bk.
020			_a3527673032 _qelectronic bk.
020			_z9783527335824 _q(print ; _qalk. paper)
020			_z352733582X _q(print ; _qalk. paper)
024	7		_a10.1002/9783527673025 _2doi
029	1		_aGBVCP _b83642624X
029	1		_aDEBBG _bBV043397671
035			_a(OCoLC)905991359 _z(OCoLC)910983561
040			_aEBLCP _beng _erda _epn _cEBLCP _dOCLCO _dRECBK _dOCLCQ _dYDXCP _dOCLCO _dN$T _dIDEBK _dDG1 _dOCLCF _dCOO _dN$T _dQGK _dDEBBG _dKSU
049			_aMAIN
050		4	_aRM301.25 _b.T44 2015eb
060		4	_aW1 _bME9613h v.65 2015
060		4	_aQV 745
072		7	_aMED _x071000 _2bisacsh
082	0	4	_a615.19 _223
245	0	0	_aThermodynamics and kinetics of drug binding / _cedited by György M. Keserü and David C. Swinney. _h[electronic resource]
264		1	_aWeinheim, Germany : _bWiley-VCH Verlag GmbH & Co. KGaA, _c[2015]
300			_a1 online resource (xxiii, 334 pages) : _billustrations (some color)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aMethods and principles in medicinal chemistry ; _vvolume 65
504			_aIncludes bibliographical references and index.
520			_a"This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors."-- _cPublisher's info.
588	0		_aDescription based on print version record.
650		0	_aDrug development.
650		0	_aBinding sites (Biochemistry) _xThermodynamics.
650		0	_aPharmacokinetics.
650		7	_aMEDICAL / Pharmacology _2bisacsh
650		7	_aBinding sites (Biochemistry) _xThermodynamics. _2fast _0(OCoLC)fst00831877
650		7	_aDrug development. _2fast _0(OCoLC)fst00898670
650		7	_aPharmacokinetics. _2fast _0(OCoLC)fst01060250
650	1	2	_aDrug Discovery.
650	1	2	_aReceptors, Drug.
650	2	2	_aLigands.
650	2	2	_aThermodynamics.
650	2	2	_aPharmacokinetics.
655		4	_aElectronic books.
655		0	_aElectronic books.
700	1		_aKeserü, G. M., _eeditor.
700	1		_aSwinney, David Carl, _eeditor.
776	0	8	_iPrint version: _tThermodynamics and kinetics of drug binding _z9783527335824 _w(OCoLC)910103973
830		0	_aMethods and principles in medicinal chemistry ; _vv. 65.
856	4	0	_uhttp://onlinelibrary.wiley.com/book/10.1002/9783527673025 _zWiley Online Library
942			_2ddc _cBK
999			_c207966 _d207966