000 02238nam a22003138a 4500
001 CR9780511976117
003 UkCbUP
005 20171019154626.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 101011s2011||||enk s ||1 0|eng|d
020 _a9780511976117 (ebook)
020 _z9780521887212 (hardback)
040 _aUkCbUP
_cUkCbUP
_erda
082 0 0 _a616.99/4
_222
245 0 0 _aCancer Metastasis :
_bBiologic Basis and Therapeutics /
_cEdited by David Lyden, Danny R. Welch, Bethan Psaila.
264 1 _aCambridge :
_bCambridge University Press,
_c2011.
300 _a1 online resource (660 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 09 Oct 2015).
520 _aMetastasis is responsible for a large burden of morbidity and mortality among cancer patients, and currently few therapies specifically target metastatic disease. Further scientific dissection of the underlying pathways is required to pave the way for new therapeutic targets. This groundbreaking new text comprehensively covers the processes underlying cancer metastasis and the clinical treatment of metastatic disease. Whereas previous volumes have been compendia of laboratory research articles, the internationally renowned authors of this volume have summarized the state-of-the-art research in the metastasis field. A major section covers the cellular and molecular pathways of metastasis and experimental techniques and the systems and models applied in this field. Subsequently, the clinical aspects of the major cancer types are considered, focusing on disease-specific research and therapeutic approaches to metastatic disease. The focus is on novel pathophysiological insights and emerging therapies; future directions for research and unmet clinical needs are also discussed.
700 1 _aLyden, David,
_eeditor of compilation.
700 1 _aWelch, Danny R. ,
_eeditor of compilation.
700 1 _aPsaila, Bethan,
_eeditor of compilation.
776 0 8 _iPrint version:
_z9780521887212
856 4 0 _uhttp://dx.doi.org/10.1017/CBO9780511976117
999 _c228058
_d228058