000 | 02215nam a22003618a 4500 | ||
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001 | CR9780511973888 | ||
003 | UkCbUP | ||
005 | 20180107143414.0 | ||
006 | m|||||o||d|||||||| | ||
007 | cr|||||||||||| | ||
008 | 101011s2011||||enk s ||1 0|eng|d | ||
020 | _a9780511973888 (ebook) | ||
020 | _z9780521517713 (hardback) | ||
020 | _z9780521734448 (paperback) | ||
040 |
_aUkCbUP _cUkCbUP _erda |
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050 | 0 | 0 |
_aRS419.5 _b.Z43 2011 |
082 | 0 | 0 |
_a615/.19 _222 |
100 | 1 |
_aZhang, Xiaohua Douglas, _eauthor. |
|
245 | 1 | 0 |
_aOptimal High-Throughput Screening : _bPractical Experimental Design and Data Analysis for Genome-Scale RNAi Research / [electronic resource] _cXiaohua Douglas Zhang. |
264 | 1 |
_aCambridge : _bCambridge University Press, _c2011. |
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300 |
_a1 online resource (232 pages) : _bdigital, PDF file(s). |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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500 | _aTitle from publisher's bibliographic system (viewed on 09 Oct 2015). | ||
520 | _aThis concise, self-contained and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound basis. Combining ideas from biology, computing and statistics, the author explains experimental designs and analytic methods that are amenable to rigorous analysis and interpretation of RNAi HTS experiments. The opening chapters are carefully presented to be accessible both to biologists with training only in basic statistics and to computational scientists and statisticians with basic biological knowledge. Biologists will see how new experiment designs and rudimentary data-handling strategies for RNAi HTS experiments can improve their results, whereas analysts will learn how to apply recently developed statistical methods to interpret HTS experiments. | ||
650 | 0 | _aHigh throughput screening (Drug development) | |
650 | 0 | _aSmall interfering RNA | |
650 | 0 | _aExperimental design | |
650 | 0 | _aRNA Interference | |
776 | 0 | 8 |
_iPrint version: _z9780521517713 |
856 | 4 | 0 |
_uhttp://dx.doi.org/10.1017/CBO9780511973888 _zCambridge Books Online |
999 |
_c236616 _d236616 |