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001 ocn908103132
003 OCoLC
005 20190328114811.0
006 m o d
007 cr mn|||||||||
008 150428s2015 enka ob 001 0 eng d
040 _aN$T
_beng
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_epn
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015 _aGBB688723
_2bnb
015 _aGBB531425
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016 7 _a017514141
_2Uk
016 7 _a017852895
_2Uk
016 7 _a101663559
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019 _a981862499
_a1066459614
020 _a9780124115255
_q(electronic bk.)
020 _a012411525X
_q(electronic bk.)
020 _z9780124115088
_q(paperback)
020 _z012411508X
_q(paperback)
035 _a(OCoLC)908103132
_z(OCoLC)981862499
_z(OCoLC)1066459614
050 4 _aRM301.25
_b.B53 2015eb
060 0 0 _a2015 G-397
060 1 0 _aQV 745
072 7 _aMED
_x071000
_2bisacsh
082 0 4 _a615/.19
_223
084 _a44.38
_2bcl
100 1 _aBlass, Benjamin E.,
_eauthor.
245 1 0 _aBasic principles of drug discovery and development /
_h[electronic resource]
_cBenjamin E. Blass.
264 1 _aAmsterdam :
_bElsevier/AP, Academic Press is an imprint of Elsevier,
_c2015
300 _a1 online resource (xv, 574 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
588 0 _aOnline resource; title from PDF title page (EBSCO, viewed October 9, 2017)
504 _aIncludes bibliographical references.
505 0 _aDrug discovery and development: an overview of modern methods and principles -- The drug discovery process: from ancient times to the present day -- Classical targets in drug discovery -- In vitro screening systems -- Medicinal chemistry -- In vitro ADME and In vivo pharmacokinetics -- Animal models of disease states -- Safety and toxicology -- Basics of clinical trials -- Translational medicine and biomarkers -- Organizational considerations and trends in the pharmaceutical industry -- Intellectual property and patents in drug discovery -- Case studies in drug discovery.
520 _aBasic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. The text introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, medicin.
650 0 _aDrug development.
650 0 _aDrugs
_xDesign.
650 7 _aMEDICAL / Pharmacology.
_2bisacsh
650 7 _aDrug development.
_2fast
_0(OCoLC)fst00898670
650 7 _aDrugs
_xDesign.
_2fast
_0(OCoLC)fst00898790
650 7 _aChimie pharmaceutique.
_2ram
650 7 _aChimie bioorganique.
_2ram
650 7 _aPharmacologie mol�eculaire.
_2ram
650 7 _aM�edicaments
_xConception.
_2ram
650 1 2 _aDrug Discovery.
650 2 2 _aDrug Evaluation.
655 4 _aElectronic books.
655 0 _aElectronic book.
776 0 8 _iPrint version:
_aBlass, Benjamin E.
_tBasic principles of drug discovery and development.
_b[Enhanced Credo edition]
_dAmsterdam [Netherlands] ; Boston [Massachusetts] : Elsevier/AP, Academic Press is an imprint of Elsevier, [2015]
_z9781785397875
_w(OCoLC)948018410
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780124115088
999 _c247078
_d247078