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005 20190328114812.0
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008 150709s2015 ne o 001 0 eng d
040 _aN$T
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019 _a914151782
_a1066493623
020 _a9780124115279
_q(electronic bk.)
020 _a0124115276
_q(electronic bk.)
020 _z9780124114982
020 _z0124114989
035 _a(OCoLC)913513717
_z(OCoLC)914151782
_z(OCoLC)1066493623
050 4 _aQD262
072 7 _aSCI
_x013040
_2bisacsh
082 0 4 _a547.2
_223
100 1 _aD'Angelo, John,
_eauthor.
245 1 0 _aHybrid retrosynthesis : organic synthesis using Reaxys and SciFinder /
_h[electronic resource]
_cJohn D'Angelo, Michael B. Smith.
264 1 _aAmsterdam, Netherlands :
_bElsevier,
_c2015
264 4 _c�2015
300 _a1 online resource (xvii, 155 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aIncludes index.
588 0 _aVendor-supplied metadata.
505 0 _aFront Cover; Hybrid Retrosynthesis; Copyright Page; Contents; Preface; Common Abbreviations; Summary of Reactions in Chapter 8; 1 Disconnections and Synthesis; 1.A The Disconnection Approach; 1.B Functional Group Exchange Reactions; 2 Making Carbon-Carbon Bonds; 3 Computer-Assisted Syntheses; 4 A Hybrid Retrosynthesis Approach; 5 Creative Strategies to Searching for Reagents; 6 Stereochemistry; 7 Molecules of Greater Complexity; 7.A Convergent Syntheses; 7.B Perovskone; 7.C Amphotericin B; 7.D Carbovir; 8 Common Fundamental Reactions in Organic Chemistry.
505 8 _a8.A Functional Group Exchange ReactionsAcetals and Ketals; 1 From Aldehydes or Ketones; Acid Chlorides; 2 From Carboxylic Acids; Alcohols; 3 From Acid Derivatives (acid chlorides, anhydrides, esters); 4 From Alkenes; 5 From Ethers; 6 From Ketones or Aldehydes; Alcohol-Alcohol; Alcohols-Functionalized; 7 From Epoxides or Alkenes; Aldehydes or Ketones; 8 From Acetals; 9 From Alcohols; 10 From Alkenes; 11 From Alkynes; 12 From Diols; 13 From Nitriles; Alkanes; 14 From Alkenes; 15 From Alkyl Halides; 16 From Ketones or Aldehydes; Alkenes; 17 From Alkynes.
505 8 _a18 From Halides, Sulfonate Esters, or Ammonium SaltsAlkyl Halides; Alkynes; 19 From Alkenyl Halides; Amides; 20 From Acid Derivatives; 21 From Nitriles; Amines; 22 From Azides, Imides, and Halides; 23 From Nitriles; 24 From Nitro Compounds; Anhydrides; 25 From Carboxylic Acids and Acid Derivatives; Aryl Halides; Carboxylic Acids; 26 From Acid Derivatives (acid chlorides, anhydrides, esters, amides); 27 From Alcohols; 28 From 1,3-Dicarboxylic Acids; 29 From Nitriles; Dienes; 30 From Aromatics; Dihalides; Diols; 31 From Alkenes; 32 From Epoxides; Enamines; 33 From Ketones or Aldehydes; Epoxides.
505 8 _a34 From Alkenes35 From Halohydrins; Esters; 36 From Carboxylic Acids and Acids Derivatives; 37 From Ketones; Ethers; 38 From Alcohols; Halides (Alkyl); 39 From Alcohols; 40 From Alkanes and Aryls; 41 From Alkenes; 42 From Alkyl Halides; Halides (Alkenyl); 43 From Alkynes; Imines; 44 From Ketones or Aldehydes; Ketals; Ketones or Aldehydes. See Aldehydes; 45 From Alkynes; 46 From Diols; 47 From Ketone-Acids; Nitriles; 48 From Amides; Nitro Compounds; 49 From Aromatics; Organometallics; 50 From Alkyl Halides; Phenols; 51 From Aryl Halides; Phosphonium Salts; 52 From Alkyl Halides; Sulfonic Acids.
505 8 _a53 From Aromatics8.B Carbon-Carbon Bond Forming Reactions; Alcohols; 54 From Acid Derivatives and Organometallics; 55 From Epoxides; 56 From Ketones or Aldehydes and Organometallics; Alcohols-Esters; 57 From Esters; Alcohol-Ketones; Aldehydes and Ketones; 58 From Aldehydes or Ketones and Alkyl Halides; 59 From Organometallics and Dimethylformamide (DMF); Aldehyde-Alkenes; 60 From Allylic Vinyl Ethers; Alkanes; 61 From Alkenes; 62 From Alkyl Halides and Organometallics; Alkenes; 63 From Alkenes and Aryl Halides (Heck reaction); 64 From Alkenes and Dienes; 65 From Dienes.
520 _aOrganic Synthesis and Retrosynthesis: An Applied Approach provides readers with the essential skills they need for both organic synthesis and retrosynthesis, encouraging their practice in real-life problems included within the text. It is designed to supplement existing organic textbooks, not only providing a refresher on organic chemistry, but also taking the subject one-step further by including practical applied examples to try in Reaxys (www.reaxys.com). In addition, the text provides new, applied skills and tools to help users during organic synthesis courses, and is also useful fo.
650 0 _aOrganic compounds
_xSynthesis.
650 0 _aChemistry, Organic
_vDatabases.
650 0 _aChemical reactions
_vDatabases.
650 7 _aSCIENCE
_xChemistry
_xOrganic.
_2bisacsh
650 7 _aChemical reactions.
_2fast
_0(OCoLC)fst00853176
650 7 _aChemistry, Organic.
_2fast
_0(OCoLC)fst00853501
650 7 _aOrganic compounds
_xSynthesis.
_2fast
_0(OCoLC)fst01047668
655 4 _aElectronic books.
655 4 _aElectronic books
_xDatabases.
655 7 _aDatabases.
_2fast
_0(OCoLC)fst01411643
655 0 _aElectronic book.
700 1 _aSmith, Michael,
_d1946 October 17-
_eauthor.
776 0 8 _iPrint version:
_aSmith, Michael B.
_tHybrid Retrosynthesis : Organic Synthesis using Reaxys and SciFinder.
_dBurlington : Elsevier Science, �2015
_z9780124114982
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780124114982
999 _c247112
_d247112