000 | 04960cam a2200577Ii 4500 | ||
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001 | ocn933611305 | ||
003 | OCoLC | ||
005 | 20190328114813.0 | ||
006 | m o d | ||
007 | cr cnu|||unuuu | ||
008 | 160104s2016 enk ob 001 0 eng d | ||
040 |
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019 |
_a933783161 _a935256261 |
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020 |
_a9780128011744 _qelectronic bk. |
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020 |
_a0128011742 _qelectronic bk. |
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020 | _z0128009640 | ||
020 | _z9780128009642 | ||
035 |
_a(OCoLC)933611305 _z(OCoLC)933783161 _z(OCoLC)935256261 |
||
050 | 4 |
_aQR201.V55 _bV53 2016eb |
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060 | 4 | _aQZ 65 | |
082 | 0 | 4 |
_a616.9/2507 _220 |
245 | 0 | 0 |
_aViral pathogenesis : from basics to systems biology / _h[electronic resource] _cedited by Michael G. Katze, Department of Microbiology, University of Washington, Seattle, WA, USA, [and 3 others]. |
250 | _a3rd ed. | ||
264 | 1 |
_aLondon, UK : _bAcademic Press, _c2016. |
|
300 | _a1 online resource. | ||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bhtml _2rda |
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490 | 1 | _aR2 digital library | |
504 | _aIncludes bibliographical references and index. | ||
588 | 0 | _aVendor-supplied metadata. | |
520 | _aViral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. | ||
505 | 0 | _aPart I: History and essentials of viral pathogenesis -- 1. The human toll of viral diseases / Neal Nathanson -- 2. Historical roots / William C. Summers -- 3. Basic concepts / Robert W. Doms -- 4. Innate immunity / Christine A. Biron -- 5. Adaptive immunity / E. John Wherry and David Masopust -- 6. Aberrant immunity / E. John Wherry and David Masopust -- 7. Patterns of infection / Neal Nathanson and Francisco Gonz�alez-Scarano -- 8. Viral oncogenesis / Nicholas A. Wallace and Denise A. Galloway -- 9. HIV and AIDS / Guido Silvestri and Emily K. Cartwright -- 10. Animal models / Victoria K. Baxter and Diane E. Griffin -- Part II: Systems-level approaches to viral pathogenesis -- 11. Systems virology / Marcus J. Korth and G. Lynn Law -- 12. The virus-host interactome / Monika Schneider, Jeffery R. Johnson, Nevan J. Krogan and Sumit K. Chanda -- 13. Host genetics / Martin T. Ferris, Mark T. Heise and Ralph S. Baric -- 14. Metabolomics and lipidomics / Priscilla L. Yang -- 15. Mathematical modeling / Alan S. Perelson -- Part III: Emergence and control of viral infections -- 16. Emerging viral diseases / James W. Le Duc and Neal Nathanson -- 17. Viral evolution / Adi Stem and Raul Andino -- 18. Viral epidemiology / Kaitlin Rainwater-Lovett, Isabel Rodriguez-Barraquer and William J. Moss -- 19. Viral vaccines / Juliet Morrison and Stanley Plotkin -- 20. Antiviral therapy / Douglas D. Richman and Neal Nathanson -- Part IV: Prizes and predictions for viral pathogenesis -- 21. Breakthrough / Neal Nathanson -- 22. What lies ahead? | |
650 | 0 |
_aVirus diseases _xPathogenesis. |
|
650 | 7 |
_aHEALTH & FITNESS / Diseases / General _2bisacsh |
|
650 | 7 |
_aMEDICAL / Clinical Medicine _2bisacsh |
|
650 | 7 |
_aMEDICAL / Diseases _2bisacsh |
|
650 | 7 |
_aMEDICAL / Evidence-Based Medicine _2bisacsh |
|
650 | 7 |
_aMEDICAL / Internal Medicine _2bisacsh |
|
650 | 7 |
_aVirus diseases _xPathogenesis. _2fast _0(OCoLC)fst01167751 |
|
650 | 1 | 2 |
_aViruses _xpathogenicity. |
650 | 2 | 2 |
_aVirus Diseases _xetiology. |
650 | 2 | 2 |
_aVirus Diseases _ximmunology. |
655 | 0 | _aElectronic books. | |
655 | 4 | _aElectronic books. | |
700 | 1 |
_aKatze, Michael G., _eeditor. |
|
776 | 0 | 8 |
_cOriginal _z0128009640 _z9780128009642 _w(DLC) 2015946371 _w(OCoLC)944946460 |
830 | 0 | _aR2 digital library. | |
856 | 4 | 0 |
_3ScienceDirect _uhttp://www.sciencedirect.com/science/book/9780128009642 |
999 |
_c247270 _d247270 |