000 04960cam a2200577Ii 4500
001 ocn933611305
003 OCoLC
005 20190328114813.0
006 m o d
007 cr cnu|||unuuu
008 160104s2016 enk ob 001 0 eng d
040 _aN$T
_beng
_erda
_epn
_cN$T
_dN$T
_dOPELS
_dOCLCF
_dUIU
_dYDXCP
_dEBLCP
_dCOO
_dCQ$
_dIDEBK
_dUSU
_dCSA
_dLVT
_dS4S
_dZ5A
_dVGM
_dOCLCO
_dMERER
_dOCLCO
_dOCLCQ
_dOCLCA
_dU3W
_dUSU
_dOCLCQ
_dD6H
_dFQM
_dOCLCO
_dAU@
_dOCLCO
019 _a933783161
_a935256261
020 _a9780128011744
_qelectronic bk.
020 _a0128011742
_qelectronic bk.
020 _z0128009640
020 _z9780128009642
035 _a(OCoLC)933611305
_z(OCoLC)933783161
_z(OCoLC)935256261
050 4 _aQR201.V55
_bV53 2016eb
060 4 _aQZ 65
082 0 4 _a616.9/2507
_220
245 0 0 _aViral pathogenesis : from basics to systems biology /
_h[electronic resource]
_cedited by Michael G. Katze, Department of Microbiology, University of Washington, Seattle, WA, USA, [and 3 others].
250 _a3rd ed.
264 1 _aLondon, UK :
_bAcademic Press,
_c2016.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bhtml
_2rda
490 1 _aR2 digital library
504 _aIncludes bibliographical references and index.
588 0 _aVendor-supplied metadata.
520 _aViral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology.
505 0 _aPart I: History and essentials of viral pathogenesis -- 1. The human toll of viral diseases / Neal Nathanson -- 2. Historical roots / William C. Summers -- 3. Basic concepts / Robert W. Doms -- 4. Innate immunity / Christine A. Biron -- 5. Adaptive immunity / E. John Wherry and David Masopust -- 6. Aberrant immunity / E. John Wherry and David Masopust -- 7. Patterns of infection / Neal Nathanson and Francisco Gonz�alez-Scarano -- 8. Viral oncogenesis / Nicholas A. Wallace and Denise A. Galloway -- 9. HIV and AIDS / Guido Silvestri and Emily K. Cartwright -- 10. Animal models / Victoria K. Baxter and Diane E. Griffin -- Part II: Systems-level approaches to viral pathogenesis -- 11. Systems virology / Marcus J. Korth and G. Lynn Law -- 12. The virus-host interactome / Monika Schneider, Jeffery R. Johnson, Nevan J. Krogan and Sumit K. Chanda -- 13. Host genetics / Martin T. Ferris, Mark T. Heise and Ralph S. Baric -- 14. Metabolomics and lipidomics / Priscilla L. Yang -- 15. Mathematical modeling / Alan S. Perelson -- Part III: Emergence and control of viral infections -- 16. Emerging viral diseases / James W. Le Duc and Neal Nathanson -- 17. Viral evolution / Adi Stem and Raul Andino -- 18. Viral epidemiology / Kaitlin Rainwater-Lovett, Isabel Rodriguez-Barraquer and William J. Moss -- 19. Viral vaccines / Juliet Morrison and Stanley Plotkin -- 20. Antiviral therapy / Douglas D. Richman and Neal Nathanson -- Part IV: Prizes and predictions for viral pathogenesis -- 21. Breakthrough / Neal Nathanson -- 22. What lies ahead?
650 0 _aVirus diseases
_xPathogenesis.
650 7 _aHEALTH & FITNESS / Diseases / General
_2bisacsh
650 7 _aMEDICAL / Clinical Medicine
_2bisacsh
650 7 _aMEDICAL / Diseases
_2bisacsh
650 7 _aMEDICAL / Evidence-Based Medicine
_2bisacsh
650 7 _aMEDICAL / Internal Medicine
_2bisacsh
650 7 _aVirus diseases
_xPathogenesis.
_2fast
_0(OCoLC)fst01167751
650 1 2 _aViruses
_xpathogenicity.
650 2 2 _aVirus Diseases
_xetiology.
650 2 2 _aVirus Diseases
_ximmunology.
655 0 _aElectronic books.
655 4 _aElectronic books.
700 1 _aKatze, Michael G.,
_eeditor.
776 0 8 _cOriginal
_z0128009640
_z9780128009642
_w(DLC) 2015946371
_w(OCoLC)944946460
830 0 _aR2 digital library.
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780128009642
999 _c247270
_d247270