000 06041cam a2200577Ki 4500
001 ocn946998430
003 OCoLC
005 20190328114815.0
006 m o d
007 cr cnu---unuuu
008 160420s2016 enk ob 001 0 eng d
040 _aOPELS
_beng
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019 _a946606061
_a946705535
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_a957679746
_a957954785
_a1066690565
020 _a0128020369
_q(electronic bk.)
020 _a9780128020364
_q(electronic bk.)
020 _a0128019999
020 _a9780128019993
020 _z9780128019993
020 _z0128019999
024 3 _a9780128019993
035 _a(OCoLC)946998430
_z(OCoLC)946606061
_z(OCoLC)946705535
_z(OCoLC)948378301
_z(OCoLC)957679746
_z(OCoLC)957954785
_z(OCoLC)1066690565
050 4 _aQP624
_b.T75 2016
060 4 _aQU 58.5
072 7 _aSCI
_x007000
_2bisacsh
082 0 4 _a572.8/6
_223
100 1 _aTseytlin, Yakov M.,
_eauthor.
245 1 0 _aAdvanced mechanical models of DNA elasticity /
_h[electronic resource]
_cYakov M. Tseytlin.
264 1 _aLondon, UK :
_bAcademic Press is an imprint of Elsevier,
_c2016.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
520 _aAdvanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic conditions on the persistence length, and dynamics with viscosity influence. It then addresses the need to understand the nature of the non-linear overstretching transition of DNA under force and why DNA has a negative twist-stretch coupling.
500 _aIncludes index.
588 0 _aOnline resource; title from PDF title page (ScienceDirect, viewed April 20, 2016).
504 _aIncludes bibliographical references and index.
505 0 _aCover; Title Page; Copyright Page; Dedication; Contents; Biography; Preface; Acknowledgments; Chapter 1 -- DNA Molecules Mechanical Properties and Models; 1.1 -- Mechanical properties; 1.2 -- Discrete, flexible chains, and atomistic models: WLC, FJC, DPC, WLRC, HW, ZZM; 1.3 -- Continuum and approximation models; 1.4 -- Dynamics and fluctuation; 1.5 -- Persistence length features; 1.6 -- A, B, Z DNA forms, S- and P-DNA phases; 1.7 -- Polymer materials; 1.8 -- DNA technical applications; 1.9 -- DNA size and mass conversion; 1.10 -- Deflection at equilibrium; References.
505 8 _aChapter 2 -- Force Application, Measurement, and Manipulation Accessories2.1 -- Stretching micropipette, glass microneedles, and hydrodynamics; 2.2 -- Optical trap and tweezers; 2.2.1 -- The Radiation Pressure of Light; 2.2.2 -- Experimental Test; 2.3 -- Small-angle X-ray scattering interference (SAXSI); 2.4 -- Magnetic tweezers; 2.4.1 -- Magnetic Influence Field; 2.4.2 -- Magnetostriction; 2.5 -- Atomic force microscopy; 2.5.1 -- Micro-Nano-Cantilevers; 2.5.2 -- Cantilever Preferred Shape; 2.5.3 -- Effective Mass Factor; 2.5.4 -- The Largest Attainable Natural Frequencies; 2.5.5 -- Spring Constants.
505 8 _a2.5.6 -- AFM Dynamics Parameters2.5.7 -- Contact Dynamics of Tapping Mode; 2.5.8 -- Nanocontact Mechanics in Manipulation; 2.6 -- Concave notch hinges; 2.6.1 -- Inverse Conformal Mapping of Approximating Contour; 2.6.2 -- Circular Notch Hinge; 2.6.3 -- Elliptical Notch Hinge; 2.6.4 -- Computerized Approximation of Concave Contours; 2.6.5 -- Instantaneous Center of Rotation; 2.6.6 -- Segmented Hinges; References; Chapter 3 -- AFM with Higher Mode Oscillations and Higher Sensitivity; 3.1 -- Effects of the resonance modes. Kinetostatic method; 3.1.1 -- Vibrating Beams; 3.1.1.1 -- Free End Cantilever.
505 8 _a3.1.1.2 -- Both Sides Clamped Beam3.1.1.3 -- Clamped-Supported Beam; 3.1.1.4 -- End Concentrated Mass; 3.2 -- Effective spring constants ratio; 3.3 -- Cantilever end inclination spring constants; 3.4 -- Quality factor influence; 3.4.1 -- AFM Tapping Mode Dynamics in Liquid; 3.5 -- End extended mass (V-shaped cantilever); 3.5.1 -- Outline of the Theory. Boundary Conditions; 3.5.2 -- Frequency Equation; 3.5.3 -- Ratios of Spring Constants; 3.5.3.1 -- Transformation of the Constituent Beam's Flexural Rigidity; 3.5.3.2 -- Spring Constant of Triangular (Trapezoid) Part.
505 8 _a3.5.4 -- Sensitivity to Additional Mass at Higher Modes3.6 -- Shift of resonant frequency; 3.7 -- Actuators and detectors; 3.7.1 -- Nanotubes (Hollow Cylinders); 3.7.2 -- Nonlocal and Asymmetric Elasticity; 3.7.2.1 -- Nonlocal Elasticity; 3.7.2.2 -- Asymmetric Elasticity; 3.8 -- Internal and external damping; 3.8.1 -- Ambient Influence and Protection; 3.8.1.1 -- Minimization of the Temperature Influence. Temperature Specified Parameters; 3.8.1.2 -- Heated Tip AFM Cantilevers; 3.8.1.3 -- Microcantilever Tip Thermal Oscillation; 3.8.2 -- Methods for the Design of Vibro-Isolation Means.
505 8 _a3.8.2.1 -- Acoustic Noise.
650 0 _aDNA.
650 2 _aDNA.
_0(DNLM)D004247
650 7 _aSCIENCE
_xLife Sciences
_xBiochemistry.
_2bisacsh
650 7 _aDNA.
_2fast
_0(OCoLC)fst00886555
655 0 _aElectronic book.
655 4 _aElectronic books.
776 0 8 _iPrint version:
_aTseytlin, Yakov M.
_tAdvanced mechanical models of DNA elasticity.
_dLondon, UK : Academic Press is an imprint of Elsevier, 2016
_z9780128019993
_z0128019999
_w(OCoLC)932174324
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780128019993
999 _c247320
_d247320