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Drug transporters : molecular characterization and role in drug disposition / [electronic resource]

by You, Guofeng [editor.]; Morris, Marilyn Emily [editor.].
Material type: materialTypeLabelBookSeries: Wiley series in drug discovery and development: Publisher: Hoboken, New Jersey : John Wiley & Sons, Inc., [2014]Edition: Second edition.Description: 1 online resource.ISBN: 9781118705049 (pdf); 1118705041 (pdf); 9781118705209 (epub); 1118705203 (epub); 9781118705308; 1118705300; 9781118704981; 1118704983; 1118489934; 9781118489932.Uniform titles: Drug transporters (2007).Subject(s): Carrier proteins | Drug carriers (Pharmacy) | SCIENCE -- Life Sciences -- Anatomy & Physiology | Carrier proteins | Drug carriers (Pharmacy) | Biological Transport -- physiology | Membrane Transport Proteins -- physiology | Pharmacokinetics | Pharmakokinetik | Arzneimittel | Chemische Synthese | Arzneimittelwechselwirkung | Electronic books | Electronic booksOnline resources: Wiley Online Library
Contents:
Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development.
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Includes bibliographical references and index.

Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development.

Description based on print version record and CIP data provided by publisher.

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Last Updated on September 15, 2019
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